Project Grant R25AG095002
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $344,164 project grant to Northwestern University to develop "M4: Modules on Advanced Methodology When Modeling Multinational Data." The primary objectives are to: 1) create a training program in large-scale data analysis for the next generation of researchers, 2) instruct trainees on protective behavioral and social factors related to Alzheimer's disease and related dementias...
- The National Institute on Aging (NIA) awarded a $377,280 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The Feinstein Institutes For Medical Research. The grant, titled "STAGE TRIALS: STAGE-MODEL TRAINING APPROACHES FOR GUIDING EFFECTIVE TRANSLATION OF BEHAVIORAL RESEARCH INTERVENTIONS IN AGING TRIALS", will develop and deliver a short-term curriculum to educate the scientific workforce on applying the NIH STAGE model to advance behavioral intervention...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $493,964 Project Grant under the Aging Research federal grant program (CFDA 93.866) to Aromha Inc. on September 10, 2025. The grant will fund the development and evaluation of a digital, self-administered, multilingual olfactory test battery called the AROMHA Brain Health Test. The goal is to create an at-home screening tool to detect early signs of Lewy body disease, which is present in up...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $320,511 project grant to TRU Diagnostics Inc. to develop a novel diagnostic tool for chronic diseases. The project aims to create a "non-stochastic W function epigenomic roadmap" using systems-based dynamic modeling to capture the shifting homeostatic set points of epigenetic markers over time. This transformative approach aims to enable personalized, dynamic health forecasts...
- The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $1,249,957 Project Grant under CFDA 93.866 (Aging Research) to Advantage Therapeutics, Inc. in Florida. The grant aims to perform IND-enabling studies on a small molecule that is disease-modifying, low-cost, and has a long safety record for the treatment of Alzheimer's disease. The proposed molecule is designed to reduce brain inflammation and restore phagocytosis, thereby improving the...
- The University of Maryland, Baltimore (UMB) was awarded a $269,025 Project Grant by the National Institute on Aging (CFDA 93.866 - Aging Research) to develop the Entrepreneurship & Science Communication for Aging and Aging-Related Research (ESCAAR) program. This program aims to train a cohort of early-career researchers in aging and aging-related diseases to effectively communicate the impact of their research to public audiences, investors, and other stakeholders. The program will be...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $1,083,046 Project Grant under the Aging Research program (CFDA 93.866) to The Johns Hopkins University. The grant, running from August 1, 2025 to July 31, 2027, will support the development of novel adeno-associated viruses (AAVs) to selectively manipulate oligodendrocyte precursor cells (OPCs) in the central nervous system. The project aims to test the hypothesis that reactive...
- The National Institute on Aging (CFDA 93.866 Aging Research) awarded a $506,000 Project Grant to the Scripps Research Institute to engineer a novel biomolecular condensate (BMC)-based tool with tunable physicochemical properties. The goal is to create an orthogonal selective autophagy receptor (SAR)-like BMC capable of supporting autophagosome biogenesis and selective cargo recruitment. This will enable detailed investigation of the biophysical regulatory mechanisms of BMCs in autophagy, which...
- The National Institute on Aging awarded a Project Grant of $455,274 to The Johns Hopkins University on May 15, 2025 under the Aging Research Federal Grant Program (CFDA 93.866). The objective of this project is to develop and apply statistical methods to improve scientific inferences in Alzheimer's disease (AD) research when using cross-sectional or longitudinal study designs. The proposed approaches aim to handle age-specific prevalent cases in case-control studies, develop regression methods...
The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded $266,174 to the Monell Chemical Senses Center on September 20, 2025 for the "Monell Scientist Entrepreneurial Program for Healthy Aging (MSEP-HA)". This project grant aims to train graduate students and postdoctoral researchers in commercializing innovations related to smell loss, which is an early biomarker of neurodegenerative diseases like Alzheimer's. The 3-week program will provide 105 hours of instruction on the biology of aging, intellectual property, regulatory pathways, and market needs identification. Six participants annually will demonstrate their commercialization interests through a presentation at Monell's Corporate Partners Symposium, and will be connected to external federal programs and local business opportunities to support their future independent biomedical ventures.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $266.2k | 9/16/25 |