Project Grant R21NS142921
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides $381,375.00 to New York University to develop genetic strategies to study a novel disinhibitory system in the cortex. Specifically, the project aims to gain a detailed understanding of how top-down and bottom-up signals are integrated in the superficial...
- This federal Project Grant award of $459,000.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to understand the anatomical and physiological changes accompanying neocortical malformations known as molecular layer heterotopia (MLH). The research will utilize GPR56 knockout mice to study the neuronal and glial changes in MLH using spatial...
- This federal Project Grant award of $401,000.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to map and model multiscale lateral interactions in the cerebral cortex that are critical for processing complex sensory information. The project aims to directly probe local lateral interactions in cortical circuits, determine...
- This Project Grant award of $637,820 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to identify novel genes responsible for proper cortical development, lamination, and axonal trajectories, as well as genes controlling the internal capsule and corticospinal tract in mice. The research will leverage forward genetics in mice to uncover new fundamental...
- This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
- The Project Grant award titled "Homeostatic Maintenance of Neocortical Excitation-Inhibition Balance by Ciliary Neuropeptidergic Signaling" was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $290,688 award will support research conducted by Brandeis University to investigate the role of primary cilia in regulating the balance of excitation...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $673,581 to New York University (NYU) to study the dynamics of the cortical-hippocampal circuit and its role in statistical learning. The goal is to build a mechanistic neurobiological circuit theory of statistical learning, which is a fundamental cognitive process enabling the...
- This federal Project Grant award of $1,270,816 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research by Yale University to decipher the gene regulatory networks controlling the development and function of radial glia, the stem cells of the human brain. The project combines cortical organoids, single cell CRISPR screens, spatial transcriptomics, and...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
The Project Grant award of $254,250 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research at New York University School of Medicine to develop genetic approaches for studying the organization and function of neocortical layer 1. This research aims to enhance understanding of how top-down and bottom-up information streams are integrated in the brain, which is critical for understanding perception, behavior, and neurological diseases such as autism and schizophrenia. The award will fund investigations into the specialized population of inhibitory interneurons in layer 1 and how they regulate top-down processing, an area that has been understudied due to the lack of molecular genetic tools. The project will run from September 2025 through August 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $254.3k | 9/25/25 |