This federal Project Grant award of $787,743 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports experimental research to investigate the brain mechanisms underlying episodic memory. The University of Chicago, the prime awardee, will use a novel non-invasive electromagnetic stimulation technique called "Hippocampal Indirectly Targeted Stimulation" (HITS)...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is funding research at The Johns Hopkins University to investigate the role of reward mechanisms in hippocampal memory formation. The $242,310 award, with a period of performance from Sep 5, 2024 to Mar 31, 2026, will support in vivo electrophysiology studies in rats to explore how reward expectation and delivery influence head scanning behavior and...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $503,887.30 to the Research Foundation For Mental Hygiene, Inc. (RFMH) at its Nathan S Kline Institute Division to conduct research aimed at elucidating the role of the supramammillary nucleus (SUM) in modulating hippocampal theta oscillations and their relationship to age-related memory dysfunction. The key objectives are to: 1) Dissect the SUM-hippocampal circuits and their physiological roles...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $571,694 to Cornell University to investigate the neural mechanisms underlying episodic memory formation and consolidation. The research aims to elucidate how temporal coordination of neuronal activity across the entorhinal cortex and hippocampus supports learning, memory recall, and predictive coding. Key activities include multi-region neural...
The National Institute of Mental Health (NIMH) awarded a $633,438 Project Grant (CFDA 93.242 - Mental Health Research Grants) to New York University (NYU) to develop a data-driven framework for real-time neural control and targeted modulation of prefrontal cortical circuits in primates. The research aims to uncover the principles governing multi-electrode microstimulation responses, introduce a novel algorithm for predicting optimal stimulation patterns to evoke specific neural activity...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the synaptic plasticity mechanisms that regulate the growth, refinement, and recovery of neural circuits underlying learning and memory. The $466,757 award, effective September 1, 2024 through August 31, 2025, will be conducted by the University of Texas at Austin. The research aims to: 1) Determine the specificity...
This $617,737 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to investigate the role of the thalamic-hippocampal pathway in the suppression and extinction of contextual fear memories associated with post-traumatic stress disorder (PTSD). The research, to be conducted by the University of Chicago, leverages a new virtual reality paradigm and advanced imaging techniques to uncover how...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will support research at Northwestern University to investigate the microcircuit mechanisms underlying distributed cortical contributions to working memory in mice. The $553,788 award, effective January 1, 2025 through December 31, 2029, will leverage advanced imaging and optogenetic techniques to compare how genetically-identified cell types in the primary...
The University of Chicago received a $3.89 million Project Grant from the National Institutes of Health National Institute of Neurological Disorders and Stroke under the 21st Century Cures Act Brain Research through Advancing Innovative Neurotechnologies program. The grant will fund research from August 2022 through August 2025 to directly measure and manipulate the spiking activity of locus coeruleus and ventral tegmental area axons in the hippocampus of mice during hippocampal-dependent...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $1,271,250 to Rockefeller University to conduct research on the molecular programs in the thalamus that enable working memory. The key objectives are to delineate the chronic and acute molecular pathways downstream of the GPR12 receptor that promote and maintain working memory function, and link this molecular activity to sustaining...