This Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $170,376 to Stanford University to develop a rapid, label-free, and cost-effective technique for quantifying chimeric antigen receptor (CAR) T cells in patient blood samples. The research aims to optimize a surface-enhanced Raman spectroscopy (SERS) approach and machine learning infrastructure to classify and enumerate engineered T cells. This will enable real-time monitoring of CAR T cell quantity throughout the therapeutic process, which is a critical indicator of efficacy and potential toxicity. The successful completion of this 2-year project, scheduled from April 2025 to March 2027, will provide a valuable tool to benefit researchers, clinicians, and patients by improving the safety and effectiveness of CAR-based immunotherapies for cancer.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $170.4k | 4/9/25 |