The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $265,650 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to HMH Hospitals Corporation, doing business as Hackensack University Medical Center, a non-profit healthcare organization in New Jersey.
The grant funds a 2-year research project to use barcode-enabled lineage tracking to elucidate the population and evolutionary dynamics of gut-colonizing Candida glabrata, a major opportunistic fungal pathogen, under antifungal drug treatment and conditions of immune dysfunction. The research aims to provide insights into how antifungal drugs and immune impairment influence the adaptation and evolution of this fungus in the gastrointestinal tract, with the goal of developing improved strategies for fungal control and reducing the emergence of drug-resistant strains.
Generated 3/4/25, 8:49 AM