Project Grant R21AI190681
Award Date
7/17/25
Completion Date
6/30/27
Dollars Obligated
$440K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Texas, USA
Similar Awards
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), provides $154,568 to support research into the antiretroviral mechanisms of the innate immune effector TRIM56. The research, conducted at Boston Children's Hospital/Harvard Medical School, aims to uncover the underlying molecular mechanisms by which TRIM56 restricts a broad range of viruses, with a focus on...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $626,423 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Texas Medical Branch at Galveston (UTMB). The funding will support research to explore the dependence of arenaviruses on the metabolism of the monosaccharides D-glucose and D-mannose, with the goal of developing carbohydrate antimetabolite compounds as potential pan-arenavirus therapeutics. Specifically,...
This federal Project Grant award of $576,501 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research by the University of Texas Medical Branch at Galveston (UTMB) on the role of the Lassa virus (LASV) NP exoribonuclease in controlling viral RNA fidelity and replication. The research aims to leverage animal models to investigate the impact of NP exonuclease function on LASV RNA mutation,...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $242,185 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Texas A&M Agrilife Research. The grant supports research to investigate the role of RNA structure in regulating developmental RNA editing in pathogenic trypanosomes, such as Trypanosoma brucei. The key objectives are to: 1) Develop a new technique to assess RNA structure under native cellular conditions versus in vitro,...
This Project Grant award, totaling $744,977.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research at Emory University to explore the role of T cells in providing protection against respiratory virus transmission. Key objectives include defining the cellular interactions and molecular mechanisms of tissue-resident memory T cells (TRM) that can limit the spread of...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $636,101 to the University of Texas Medical Branch at Galveston (UTMB) to investigate the RNA packaging mechanisms of Rift Valley Fever Virus (RVFV). The key objectives are to elucidate how the segmented RVFV genome is efficiently packaged and co-packaged into viral particles, which is critical for understanding RVFV...
This federal Project Grant award, with ID R21AI187731, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $245,895 award, granted on November 14, 2024, supports research at the Icahn School of Medicine at Mount Sinai to systematically assess the impact of ubiquitination on Flavivirus infection using CRISPR-Cas9 base editing approaches. The goal is to discover novel pathways that promote...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $640,735.00 to Emory University to conduct research on understanding the mechanisms of CD8+ tissue-resident memory T cells (TRM) that mediate protection against respiratory virus transmission. The research aims to investigate the characteristics, durability, and molecular mechanisms of respiratory tract TRM...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $185,280 to Texas A&M University System Health Science Center to investigate how the Mycobacterium tuberculosis (MTB) secreted protein Rv1075c interacts with host histone methyltransferases to promote MTB infection. The key objectives are to define changes in histone methylation at innate immune genes during MTB...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $232,800.00 to Baylor College of Medicine to conduct research on the functional characterization of viral non-polyadenylated mRNA sequences that enable mRNA stability and translation. The research aims to define the minimal functional sequences and protein binding partners of non-poly(A) 3' ends from exemplar bunyaviral mRNAs, and to screen...