The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $463,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania. The grant funds research to investigate the role of cellular senescence in severe COVID-19 outcomes, particularly in individuals with pre-existing conditions like obesity and non-alcoholic steatohepatitis (NASH). The research aims to determine if removal of senescent cells can alleviate severe COVID-19 symptoms in mouse models and cell culture experiments using human lung, adipose, and liver-derived organoid samples. The project period runs from Jul 2, 2024 to May 31, 2026.
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