The National Institute on Aging (NIA) has awarded Albany Medical College a $462,923 federal Project Grant under the Aging Research program (CFDA 93.866) to develop new mouse models of andropause, the age-related decline in male sex hormones, for studying its effects on Alzheimer's disease and related dementias. The 2-year grant aims to characterize the natural timeline of endocrine aging in several mouse models of Alzheimer's and then create two new andropause models through surgical and non-surgical methods to mimic the gradual loss of androgens observed in aging men. The goal is to establish improved preclinical models that better reflect the hormonal environment of older adults, enabling more translatable research on therapies for Alzheimer's and related disorders. As part of this project, the Research Foundation for the State University of New York (RF-SUNY) is receiving a $116,978 sub-award to collaborate on developing the andropause mouse models.
Generated 3/4/25, 5:15 AM