Project Grant R21AG088945
- The National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), awarded Adeptrix Corp. a $499,940 Project Grant on Sep 11, 2025 to develop TAUTRACE, an ultrasensitive immunoassay platform for quantifying distinct molecular forms of the tau protein in cerebrospinal fluid and plasma at femtogram/milliliter levels. This innovative technology enables the detection of single ions, allowing for the quantification of tau proteoforms as critical Alzheimer's disease...
- This $200,000 Project Grant awarded by the National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems under CFDA 47.041 (Engineering) aims to develop and implement a novel testing platform to evaluate the accuracy of wearable photoplethysmography-based blood pressure monitoring devices. The University of Maryland, College Park will construct a bench flow phantom that simulates physiologically relevant blood pressure, blood flow, anatomical, and optical...
- This Project Grant award of $499,943 from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), supports the development of a novel, unobtrusive device by Aster Labs, Inc. to continuously measure and analyze gait patterns in older Black adults as an early indicator of health decline from Alzheimer's disease and related dementias (ADRD). The device aims to provide medical professionals and caregivers with remote access to these insights to help...
- This federal Project Grant award of $649,678, provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports the development of a high-speed, wearable speckle contrast optical spectroscopy (SCOS) system for cuffless blood pressure monitoring. The project aims to convert the existing benchtop SCOS technology into a wearable device capable of multi-hour ambulatory monitoring, and to test the technique in a wider range of subjects,...
- The National Science Foundation (NSF) awarded a $347,386 Project Grant under the Engineering program (CFDA 47.041) to the University of Illinois. The grant, with a performance period from April 1, 2025 to July 31, 2026, aims to develop a novel wearable watch capable of continuously and conveniently monitoring blood pressure through the use of bioimpedance sensing technology. This technology is intended to address the need for an accurate, low-cost, and easy-to-use device for out-of-clinic...
- The Department of Health and Human Services' National Institutes of Health's National Institute on Aging awarded $865,905 under the Aging Research program (CFDA 93.866) to Careband, Inc. to develop the Appraise to Assist system. This project grant will support Careband and its partner Eperture LLC to engineer a system integrating Careband's wearable device and Eperture's tablet platform. The system aims to passively and unobtrusively monitor, empirically measure, and facilitate engagement...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $320,511 project grant to TRU Diagnostics Inc. to develop a novel diagnostic tool for chronic diseases. The project aims to create a "non-stochastic W function epigenomic roadmap" using systems-based dynamic modeling to capture the shifting homeostatic set points of epigenetic markers over time. This transformative approach aims to enable personalized, dynamic health forecasts...
- This $114,498 Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) will fund a study to investigate the construct validity of smartwatch-derived metrics for early detection of Alzheimer's disease and related dementias. The study will recruit a diverse sample of 90 participants aged 55 and older with healthy cognition or mild cognitive impairment from the Philadelphia region. Participants will wear a Garmin Vivosmart 4 smartwatch for 30 days to passively monitor...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $499,921 Project Grant to Applied Universal Dynamics, Corp to develop a system that allows off-site monitoring of pressure ulcers for patients in a rural long-term care facility. This Phase I project aims to demonstrate the feasibility of an imaging instrument that can assist individual caregivers in remotely monitoring deep pressure tissue injuries. The innovative solution combines a...
- The National Institute on Aging (NIA) awarded a $613,823 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The purpose of this 5-year grant, beginning September 1, 2025, is to assess the effectiveness of the SENSE4SAFETY technology-supported intervention in reducing fall risk for community-dwelling older adults with mild cognitive impairment. The...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) in the amount of $385,517 supports the validation of a novel wearable device called TRACE to monitor orthostatic vital signs as an alternative to the current clinical standard of blood pressure cuffs. The project aims to demonstrate that TRACE's unique blood volume-based metrics are more predictive of orthostatic symptoms than blood pressure measurements, particularly in capturing the rapid hemodynamic changes during the initial orthostatic response. The grant recipient, Wayne State University, will validate TRACE's 4 orthostatic metrics against the gold standard of transcranial Doppler perfusion measurement over the award period from August 2025 to July 2027. Successful validation of TRACE's capabilities could help address the underdiagnosis and mismanagement of orthostatic disorders, which disproportionately affect older adults.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $385.5k | 8/11/25 |