This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $551,986.00 to The Jackson Laboratory to develop an explainable unified AI strategy for efficient and robust integrative analysis of multi-omics data from heterogeneous longevity studies. The goal is to identify protective genetic variants associated with exceptional human longevity, which can inform therapeutic interventions to improve human health. The 2-year project aims to: 1) create an integrative data analysis software that models relationships among genomic markers, data modalities, and studies; 2) apply the methods to analyze Long-Life Family Study and Integrative Longevity Omics data to identify longevity-associated pathways and biomarkers; and 3) analyze omics data from human and diverse species to find conserved and species-specific longevity factors. The software developed under this award will be publicly available to support complex disease research beyond the scope of this aging-focused project.
Generated 8/13/24, 6:18 AM