Project Grant R21AG081893
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of California, Irvine $785,000 under the Cardiovascular Diseases Research program (CFDA 93.837) to develop the Maternal Obstetric Monitoring System (MOMS), a wearable device for early detection of postpartum hemorrhage (PPH). The project, which commenced September 1, 2025 and concludes July 31, 2026, addresses a critical clinical need by creating an integrated monitoring system that...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded the University of California, Irvine a $2.22 million Project Grant under the Aging Research program (CFDA 93.866) effective September 1, 2025, through August 31, 2027. This award supports the development and optimization of enhancer adeno-associated virus (AAV) vectors—genetically engineered viral tools designed to provide cell-type-specific genetic access and manipulation of brain cells implicated in aging and Alzheimer's...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of California, Irvine $617,366 on August 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop an integrated multimodal intravascular imaging system. The project, scheduled for completion by May 31, 2029, delivers the design, construction, and development of a combined Optical Coherence Tomography (OCT), Ultrasound (US), and Photoacoustic Tomography...
- Federal Grant Award Summary The National Institute on Aging awarded the University of California, Irvine a $3.22 million Project Grant under the Aging Research program (CFDA 93.866) on September 15, 2025, with a completion date of August 31, 2029. This research initiative examines the role of the retrosplenial cortex (RSC) in Alzheimer's disease (AD) pathogenesis through translational investigation combining mouse models and human studies. The primary deliverables include scientific findings...
- Federal Grant Award Summary Wayne State University received a $385,517 Project Grant award from the National Institute on Aging (Aging Research program, CFDA 93.866) effective August 15, 2025, through July 31, 2027. The award funds research to validate a novel wearable device called TRACE (an NIA award-winning technology developed by Principal Investigator Professor Amar Basu) that measures orthostatic vital signs via an earlobe sensor. The research team, which includes emergency medicine...
- Federal Grant Award Summary The National Institute on Aging awarded a $2.49 million Project Grant to the University of California, Irvine under the Aging Research program (CFDA 93.866) on September 15, 2025, with a completion date of August 31, 2029. This award supports fundamental research investigating circuit vulnerability of the lateral and medial entorhinal cortices in tauopathy models relevant to Alzheimer's disease (AD). The project will utilize two tau mouse models to identify entorhinal...
- Federal Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering awarded The Leland Stanford Junior University a $131,085 Project Grant (CFDA 93.286: Discovery and Applied Research for Technological Innovations to Improve Human Health) on June 9, 2025, with a completion date of May 31, 2027. This award supports the development of an ultrasound-interrogated implantable intracranial pressure (ICP) sensor designed to address critical limitations in hydrocephalus...
- Federal Grant Award Summary The National Institute on Aging (NIA) awarded $632,507 to the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center under the Aging Research program (CFDA 93.866) effective September 25, 2025, with completion targeted for August 31, 2030. This Project Grant supports a Type 2 hybrid effectiveness-implementation study examining the scalability and real-world implementation of Time Limited Trials (TLTs) in intensive care unit (ICU) settings. The...
- Federal Grant Award Summary The National Institute on Aging awarded a $589,154 Project Grant to the University of Maryland, Baltimore, effective February 1, 2026, through January 31, 2031, under the Aging Research program (CFDA 93.866). This award supports the development and validation of a normalized cerebrovascular reactivity (NCVR) magnetic resonance imaging technique designed to improve detection of cerebral vascular dysfunction in patients with small-vessel-disease-related cognitive...
- Federal Project Grant Award Summary Applied Universal Dynamics, Corp received a $499,921 Phase I Project Grant award dated September 20, 2025, from the National Institute on Aging under the Aging Research program (CFDA 93.866) to develop and demonstrate the feasibility of a remote monitoring system for pressure ulcers in rural long-term care facilities. The project, with a completion date of August 31, 2026, focuses on creating an innovative imaging instrument that enables untrained caregivers...
The University of California, Irvine received a $408,504 Project Grant from the National Institute on Aging (Aging Research program, CFDA 93.866) awarded February 15, 2026, with a completion date of January 31, 2028. The award funds development and validation of an Integrated Multimodal Hemodynamic Monitoring Platform (IMOMS)—a wearable device designed to detect and manage hemorrhage in trauma patients through advanced sensing and predictive analytics. The platform integrates Micro-Electro-Mechanical Systems (MEMS), Laser Speckle Imaging (LSI), and Diffuse Optical Spectroscopy (DOS) technologies to continuously monitor vital signs and hemodynamic parameters including heart rate, blood pressure, cardiac output, blood flow, oxygen saturation, and oxygen consumption. The deliverables encompass three primary research objectives: validation of the IMOMS platform in a controlled rabbit hemorrhage model to demonstrate accurate continuous measurement of hemodynamic parameters; development and refinement of a machine learning model using multimodal data streams to predict hemorrhage and identify early indicators of hypovolemia with transfer learning capability from animal to human applications; and clinical testing of the prototype and predictive model in operating room settings with high-risk surgical patients to determine monitoring accuracy and refine hemorrhage prediction capabilities across diverse patient populations. Successful completion is expected to advance trauma care outcomes and address racial disparities in hemorrhage-related mortality through enhanced early detection and intervention capabilities.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $408.5k | 2/3/26 |