This federal Project Grant award from the National Institute of Nursing Research (NINR), under CFDA program 93.361 Nursing Research, provides $441,375 to develop and evaluate an interactive mobile asthma action plan (IMAAP) to support self-management and medication adherence for adolescents with moderate to severe persistent asthma. The project will involve iterative development through user interviews, prototype testing, and a pilot randomized controlled trial with 20 adolescents using IMAAP...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), will fund a $797,130 study to evaluate implementation strategies for increasing the adoption and real-world effectiveness of Single Maintenance and Reliever Therapy (SMART) in a predominantly Black pediatric population with poorly controlled asthma. The study will use a cluster-randomized design across 18 pediatric primary care clinics...
The Project Grant award K23HL163253, totaling $178,783, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award will support Dr. Pappalardo's research to understand barriers and develop targeted implementation strategies for school-based stock inhaler programs, with the goal of improving asthma management and reducing health disparities. The grant will fund a community-engaged, implementation science...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $714,586 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the University of Arizona to develop and evaluate implementation strategies for the "Stock Albuterol for Every 'SAFE' School" program in Arizona. The goal is to enhance adoption, fidelity, and effectiveness of this school-based stock albuterol program, which provides emergency respiratory medication access for students experiencing...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, is focused on investigating the relationship between social determinants of health (SDOH) and asthma-related morbidity in Black and Latinx adults with moderate-to-severe asthma. The $274,392 award to the University of South Florida will address three specific aims: 1) determine if Black and Latinx adults have unique SDOH exposures that are...
This federal Project Grant award, R01HL177625, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award supports research to investigate the role of microRNAs in regulating airway smooth muscle function and their contribution to asthma pathogenesis. The overarching goal is to establish the in vivo role of key microRNAs in regulating airway smooth muscle phenotypes and airway hyperresponsiveness, as well as...
The federal Project Grant award K23HL174407, totaling $164,453, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds research conducted by the Arkansas Children's Research Institute (ACRI) in Little Rock, Arkansas to investigate "Multifactorial Asthma Determinants in Underresourced Pediatric Populations." This research aims to address disparities in pediatric asthma, which is more...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) will support Dr. Tyris' research to advance the integration of social and medical care for children with asthma. The $154,861 grant will enable three key aims: 1) developing a machine learning model to predict hospitalization risk among children with asthma using social adversity, clinical, and demographic data; 2) characterizing...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $755,336 Project Grant (CFDA 93.837 - Cardiovascular Diseases Research) to the Albert Einstein College of Medicine to study the influence of asthma on walking in older adults. The key objectives are to examine the neurological and behavioral processes, such as brain activation patterns and medication adherence, that may underlie the relationship between asthma and mobility impairments in older individuals. The project will...
This $347,608 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports the development of a novel, oral, once-daily immunoregulatory therapeutic for the treatment of asthma by Biotherapeutics, Inc., an emerging biotechnology company in Blacksburg, Virginia. The goal of this 1-year project is to characterize the therapeutic efficacy and route of administration of the novel drug candidate in mouse...