This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $447,337 to Ball State University to conduct research on the regulator MITONEET and its role in cellular redox homeostasis and signaling. The research aims to investigate how the electronic properties and stability of the MITONEET [2Fe-2S] cluster contribute to the metabolism of sulfur-containing molecules and the regulation of the cytosolic free iron pool, which can impact cellular processes like oxidative stress and ferroptosis. The 3-year project, running from September 1, 2024 to August 31, 2027, will advance the understanding of MITONEET as a druggable target with implications for type-2 diabetes, cancer, and Parkinson's disease.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $447.3k | 7/31/24 |