This Project Grant award, valued at $171,064.00 and effective from January 1, 2025 to June 30, 2027, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program. The objective of this research is to determine how polychlorinated biphenyls (PCBs) alter the crosstalk between adipocytes (fat cells) and macrophages (immune cells) in adipose tissue, and how this disruption contributes to endocrine and metabolic...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, supports research to investigate the impact of polychlorinated biphenyls (PCBs) exposure on the development of depression in adolescents. The $495,980 award to the University of Miami aims to study the mechanistic link between PCB exposure, gut microbiome disruption, blood-brain barrier dysfunction, and neuroinflammation leading to...
This federal Project Grant award of $695,853 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research on the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on children's development. The award will fund a collaborative effort between the Arkansas Children's Research Institute, Emory University, and the University of Kentucky Research Foundation to investigate how prenatal PFAS exposure...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113) will fund research at Northern Kentucky University (NKU) to investigate the use of maternal and offspring exercise as a means to mitigate the developmental neurotoxicity effects of prenatal exposure to benzo[a]pyrene (BaP), a known carcinogen and environmental pollutant. The $140,000 award, which runs from September 2023 to August...
This three-year $893,704 project grant from the National Institutes of Health's National Institute of Environmental Health Sciences will fund research at DePaul University to study the direct effects of polychlorinated biphenyls (PCBs) on microglial function across sexes and developmental stages. The central hypothesis is that PCB exposure will prime microglia—the resident immune cells of the brain—to produce exaggerated responses to secondary challenges in an age- and sex-specific manner. The...
The National Institutes of Health National Institute of Environmental Health Sciences awarded a $924,612 Project Grant to the California State University, East Bay Foundation, Inc. under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund research from August 2022 to July 2025 to advance chemical risk assessment and predictive toxicology through the development, validation and integration of high-throughput mechanistic in vitro assays. Specifically, the grantee will...
This $553,708 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, aims to advance the development of a community-led Zebrafish Toxicology Phenotype Atlas. The key products and services to be delivered include: Designing and deploying a standardized Toxicophenotype Data Model to improve data compatibility across zebrafish toxicology studies and domains. Creating a Toxicophenotype Annotation Toolkit to...
This $546,350 Project Grant, awarded on January 13, 2025 by the National Institute of Environmental Health Sciences (CFDA 93.113 Environmental Health), supports research to define the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The primary awardee, The Research Foundation for the State University of New York, will utilize zebrafish models to investigate PFAS uptake mechanisms, cellular impacts, and effects on neurodevelopment and behavior. A...
This Project Grant award, totaling $385,219.00, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program. The award supports research to investigate the role of albumin and other serum factors in the accumulation and toxicity of per- and polyfluoroalkyl substances (PFAS) in the body. The key objectives of this 5-year award (ending February 2030) are to: 1) determine whether albumin is a key factor for...
This $440,000 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research at Northwestern University to create an unbiased and global map of the cellular response to environmental proteotoxic stress. The project will integrate cutting-edge chemical-genetic screening with computational analysis to identify critical components, functions, and regulatory nodes in the proteostasis network that cells...