This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $474,337 to the University of Colorado-Denver to conduct research on pediatric treatment-induced high-grade gliomas, also known as radiation-induced gliomas (RIGs). The research aims to discover germline risk factors for RIGs, identify key pathways of tumor growth and treatment resistance, and test combination treatments of chemotherapies and radiation therapy using patient-derived cell culture and xenograft models. The project will run from August 15, 2024 to July 31, 2029, with the goal of improving outcomes for children affected by these fatal brain tumors caused by prior cancer treatment.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $474.3k | 8/12/24 |