Project Grant R01NS133200
Award Date
9/10/24
Completion Date
8/31/29
Dollars Obligated
$657K
Federal Agency
National Institute of Neurological Disorders and Stroke
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Cincinnati, OH 45229, USA
Similar Awards
This $877,001 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research to mechanistically define the cellular and molecular interdependencies underlying neurofibromatosis type 1 (NF1)-associated low-grade gliomas (LGGs) and neurodevelopmental deficits (NDDs). The research leverages patient-derived induced pluripotent...
The Department of Defense, through the Military Medical Research and Development program (CFDA 12.420), awarded a $858,033 Project Grant to the Children's Hospital Medical Center in Cincinnati, Ohio. The grant, titled "TARGETING SCHWANN CELL-IMMUNE INTERACTIONS IN NEUROFIBROMATOSIS TYPE 1", will fund research focused on improving treatment approaches for neurofibromatosis type 1, a genetic disorder that causes tumor growth in the nervous system. The grant award period runs from...
This $713,818 Project Grant awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports research by the Research Institute at Nationwide Children's Hospital in Columbus, Ohio to characterize novel patient-specific modeling systems for NF2 disease research and therapeutic testing. The project will be conducted from September 1, 2024 through August 31, 2027. The Research Institute has extensive experience delivering federal research...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $604,852 in funding to Childrens Hospital Medical Center in Cincinnati, OH. The grant supports research aimed at understanding the role of glial progenitor cells in the initiation and recurrence of medulloblastoma, the most common malignant childhood brain tumor. The...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $237,399 to Vanderbilt University to investigate the role of the metabotropic glutamate receptor 7 (mGlu7) as a potential genetic modifier of cognitive deficits associated with neurofibromatosis type 1 (NF1). The research aims to test the hypothesis that potentiation of mGlu7 can...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, provides $190,485.00 over the period of February 4, 2025 to January 31, 2030 to Indiana University Indianapolis to investigate the molecular mechanisms underlying differentiation failure in neuroepithelial stem cells with NF2 gene mutations. The goal is to identify the...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $444,000.00 to The University of Texas Rio Grande Valley (UTRGV) to study the impact of neurofibromatosis type 1 (NF1) gene mutations on oligodendrocyte development and fine motor learning. The 4-year project aims to use mouse models to define how NF1 mutations affect the...
This $635,173 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to understand the mechanisms by which the MYCN oncogene promotes an immunosuppressive tumor microenvironment in high-risk neuroblastoma. The research team, led by investigators at Boston University Medical Campus, will leverage zebrafish models and human patient samples...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $460,940 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The University of Texas MD Anderson Cancer Center. This 2-year grant, effective June 1, 2025, will support research to investigate how glioma-associated germline risk alleles impact neurodevelopmental trajectories. Specifically, the research will leverage single-cell and bulk profiling...
This Project Grant award, totaling $443,354.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research at the University of Pittsburgh focused on identifying and targeting metabolic dependencies in diffuse midline gliomas (DMG), a highly aggressive form of pediatric brain cancer. Specifically, the research aims to...