This Project Grant award of $2,245,812.00 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, is funding a 3-arm randomized controlled trial (RCT) to examine the effectiveness of personalized daily text message reminders, with and without financial incentives, in improving antidepressant adherence and depression symptoms for adult primary care patients. The study aims to compare these two adherence support strategies to usual care, as well as to each other, over a 52-week period. Key outcome measures include antidepressant adherence, depression symptom response, and qualitative exploration of patient perspectives to maximize the interventions' effectiveness. The award was granted on August 15, 2024, with an ultimate completion date of May 31, 2029. The principal investigator for this project is The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $714.6k | 5/22/25 | ||
| Not listed | $765.6k | 8/9/24 | ||
| Not listed | $765.6k | 8/9/24 |