Project Grant R01HL178035
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $692,742 to support research on the role of a novel hormone complex called FABKIN in regulating dyslipidemia and inflammation that contribute to atherosclerosis. The award was made to the President and Fellows of Harvard College, specifically the Harvard T.H. Chan School of Public Health, and runs from September 2025 to May 2029. The research aims to...
- The National Heart Lung and Blood Institute has awarded a $841,555 Cooperative Agreement under the Cardiovascular Diseases Research program (CFDA 93.837) to Harvard Pilgrim Health Care Inc. The "ENHANCE" project aims to integrate a nutrition enhancement within established, evidence-based, federally funded home visiting programs to promote healthier eating patterns and food access for families from lower incomes and underserved communities. The multi-level intervention will be...
- This federal Project Grant award of $1,119,410.00 was provided by the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant supports a multi-disciplinary research initiative to investigate longitudinal changes in DNA methylation (LC-DNAM) and its relationship to cardiovascular disease (CVD) risk factors and outcomes across four large population-based cohort studies - ARIC, CARDIA, FHS, and MESA. The research aims to: 1)...
- This Project Grant award of $570,814 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research by President and Fellows of Harvard College (Harvard Medical School) to investigate the spatial reach and dynamics of T-cell derived cytokines and their impact on cellular variability within tissues. The key products or services to be delivered include: Characterizing the spatial extent of T-cell derived cytokines such as interleukin-2 and...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) is funding research to discover novel biomarkers and biological mechanisms underlying early-stage heart failure (HF). The $147,486 award to Duke University will support the development of an automated computational phenotype to identify early-stage HF, which will then be applied to large population cohorts. The research aims to leverage multi-omics data integration and...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $190,491 to Beth Israel Deaconess Medical Center, Inc. to conduct research on plasma protein markers of the blood pressure response during exercise and their relation to incident hypertension and cardiovascular disease. The project aims to identify circulating proteins associated with exercise blood pressure that could serve as predictive markers for future...
- This Project Grant award of $784,362.00, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) to Brigham & Women's Hospital Inc., will support research investigating the role of body composition, coronary microvascular dysfunction, and heart failure with preserved ejection fraction in characterizing adverse cardiometabolic disease phenotypes. The research aims to leverage novel imaging technologies to identify mechanisms of...
- The federal Project Grant award of $117,525.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) is funding research at Boston Children's Hospital to investigate cellular adaptation to perturbations in one-carbon metabolism. The research aims to characterize the role of the UFMylation pathway in maintaining cellular fitness during folate depletion, and explore signaling cascades that promote cellular fitness in response to one-carbon metabolism...
- This federal Project Grant award of $708,678, provided by the National Heart, Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to conduct a Sequential Multiple Assignment Randomized Trial (SMART) to reduce food insecurity and improve adherence in patients with hypertension. The key products and services to be delivered under this grant include: Determining the most effective initial food insecurity intervention (resource information or community health worker...
- This federal Project Grant award of $306,871 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to develop an educational and actionable report-back system for individuals and healthcare providers (HCPs) to help reduce PFAS (per- and polyfluoroalkyl substances) exposure and improve cardiovascular health in rural communities. The award recipient, Million Marker Wellness Inc., will work with 20 individuals and 10 HCPs in rural Nevada to create...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $733,785.00 to President and Fellows of Harvard College, Harvard T.H. Chan School of Public Health, to conduct research on identifying and validating biomarkers of plant-rich diets and their associations with cardiovascular disease risk. The key products and services to be delivered under this grant include: 1) Assessing the dose- and time-dependent formation of flavonoid biomarkers in urine and blood through a randomized crossover trial comparing low- and high-flavonoid diets among healthy individuals, and investigating whether a flavonoid-rich diet reduces carbonyl and oxidative stress; and 2) Comprehensive profiling of urinary flavonoid metabolites to examine their relationships with carbonyl/oxidative stress biomarkers and cardiovascular disease risk in three large cohort studies. This research aims to develop improved methods for assessing adherence to plant-rich, flavonoid-rich diets and their impact on cardiometabolic health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $733.8k | 9/12/25 |