Project Grant R01HL176691

Award Date 1/1/25
Completion Date 11/30/28
Dollars Obligated $772K
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Los Angeles, CA 90095, USA

The University of California, Los Angeles, through its Office of Research Administration, has been awarded a Project Grant of $771,750.00 from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant, effective from January 1, 2025, through November 30, 2028, will support research to investigate the role of macrophages in regulating cardiac muscle metabolism following myocardial infarction. The project aims to shed novel insight into how macrophages recruited to the infarcted heart disrupt cardiac muscle energetics and identify potential therapeutic strategies for improving post-infarct heart function. This multidisciplinary research effort will leverage UCLA's expertise in cardiac metabolism, isotope-labeled metabolite tracing, nucleotide biochemistry, and cardiac physiology.

Additionally, UCLA holds an indefinite delivery contract from the Department of Veterans Affairs Veterans Health Administration, valued at up to $261,694.92, to provide animal per diem services for pigs to support VA medical research projects. A delivery order worth $56,251.80 was issued against this contract in September 2023, covering the animal services through September 2024.

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