Project Grant R01HL173312
Award Date 9/1/25
Completion Date 8/31/27
Dollars Obligated $30K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Oklahoma City, OK 73104, USA
Similar Awards
- The National Institutes of Health National Heart Lung and Blood Institute awarded a $511,680 Project Grant to the University of Illinois under the Cardiovascular Diseases Research program (CFDA 93.837). The grant will fund research from February 2021 through August 2021 to investigate mechanisms by which vascular endothelial cells instruct macrophage fate in inflammatory injury. Specifically, the research will examine how endothelial cell Wnt signaling licenses the differentiation of monocytes...
- This $169,020 five-year Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research at the University of Pennsylvania to study how endothelial cells coordinate immune responses after influenza infection and how a novel population of injury-associated capillary endothelial cells is regulated at sites of persistent lung injury. The project aims to gain expertise in endothelial-immune interactions to advance the principal...
- The University of Toledo was awarded a $579,309 Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on June 9, 2025. The grant supports research to investigate the role of cysteinyl leukotriene receptor signaling in regulating lung inflammation. The project aims to determine how the cysteinyl leukotriene receptor CYSLT1R promotes an inflammatory phenotype in macrophages, suppresses their proliferation, and influences the immune response...
- The University of Texas Southwestern Medical Center received a $772,275 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct research on how endothelial cell scavenger receptor class B type I (SR-BI) is regulated and interacts with other proteins to drive LDL transcytosis and promote atherosclerosis. The award, effective August 25, 2025 through May 31, 2029, aims to determine the mechanisms by which hypercholesterolemia and...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to support research on modulating the resolution of angiogenesis and normalizing the vasculature for therapeutic benefit in cardiovascular diseases. The $549,665 award, effective January 15, 2025 through November 30, 2028, will fund research conducted by the University of Maryland, Baltimore to investigate mechanisms that regulate the resolution of angiogenesis,...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to understand how immune cells contribute to target organ damage in hypertension and autoimmune diseases. The $3,043,800 award to Vanderbilt University Medical Center will fund research projects focused on: 1) identifying T cell antigens and receptors associated with hypertension, systemic lupus erythematosus (SLE), and psoriasis; and 2) examining how dietary salt...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $775,720 project grant to Yale University under the Cardiovascular Diseases Research federal grant program (CFDA 93.837) to conduct research on the role of endothelial protocadherins in vascular development and disease. The project aims to: 1) determine the effects of knocking out or inhibiting the protocadherin gamma (PCDHG) cluster in endothelial cells in mouse models of vascular inflammation, 2) elucidate the mechanism by which...
- The federal Project Grant award of $678,803.00 was provided by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to The Ohio State University. The funding supports research to investigate the role of the mitochondrial deubiquitinase USP30 in regulating microvascular endothelial cell function and its potential as a therapeutic target for acute inflammatory diseases like acute respiratory distress syndrome (ARDS) and sepsis. Key...
- This federal Project Grant award, valued at $583,233.00 and awarded by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to investigate the role of circulating osteopontin (OPN) and the CD44 receptor on innate immune cells in remote lung inflammation following acute kidney injury. The overall goal is to develop novel strategies to prevent or treat secondary organ complications in multi-organ failure. Key objectives include: 1) identifying lung...
- This federal Project Grant award of $701,791 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to investigate the role of neddylation, a post-translational modification, in protecting endothelial cell integrity and function. The research aims to establish the pathophysiological significance of neddylation in the endothelium and identify key downstream effectors. The University of Nebraska, Lincoln is the awardee and will utilize...