The University of Utah was awarded a $538,794 Project Grant from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to develop a novel magnetic resonance imaging (MRI) technique for improved detection of coronary artery disease in patients with atrial fibrillation. The key objectives are to: (1) develop a flow and motion insensitive steady-state ungated quantitative MRI method with simultaneous multi-slice acquisition and advanced reconstruction techniques, (2) rigorously compare the quantitative MRI perfusion measures to existing methods, and (3) validate the new approach against positron emission tomography imaging and invasive fractional flow measurements. The project aims to deliver a game-changing MRI technology that can accurately diagnose coronary artery disease in the challenging atrial fibrillation patient population, addressing a major healthcare issue affecting over 20 million Americans. The award period is from July 1, 2024 to April 30, 2028.
Generated 3/4/25, 7:50 AM