The University of California, Los Angeles (UCLA) - through its Office of Research Administration division - has been awarded a $740,037 project grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant will fund research to investigate how cardiac fibroblasts regulate angiogenesis, or new blood vessel formation, following a myocardial infarction. Specific aims include evaluating the function of anti-angiogenic factors expressed by cardiac fibroblasts, as well as determining if pro-angiogenic factor expression can enhance vascular repair and recovery. This multi-year research project, spanning from February 2025 to November 2029, aims to provide a better understanding of the cellular and molecular signals that promote vascular perfusion after a heart attack, in order to guide the development of new therapeutic approaches for ischemic heart disease.
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