Project Grant R01ES038132
- Federal Project Grant Award Summary The University of Michigan, Ann Arbor, received a $1,155,450 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded June 20, 2025, with completion targeted for March 31, 2030. The award supports mechanistic research investigating impaired epithelial regeneration and progressive lung fibrosis resulting from silica and asbestos dust inhalation. The project will examine...
- Federal Project Grant Summary Michigan State University received a $100,000 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective September 27, 2025, with a completion date of August 31, 2027. The award funds research investigating the role of the epicardium and inositol-requiring enzyme 1A (IRE1A) in mediating the effects of environmental chemical exposures on cardiac function. The research...
- Grant Award Summary The University of Michigan received a $771,168 Project Grant award, effective April 1, 2026, through the National Institute of Environmental Health Sciences (NIEHS) Environmental Health program (CFDA 93.113) to conduct a five-year research initiative examining the interplay between per- and polyfluoroalkyl substances (PFAS) and T cell epigenetics in autoimmunity and lupus. The research leverages two complementary population-based cohorts—the Michigan Lupus Epidemiology...
- Federal Grant Award Summary The University of Michigan has been awarded $760,950 under the Child Health and Human Development Extramural Research program (CFDA 93.865) by the National Institute of Child Health and Human Development (NICHD), effective July 1, 2025 through June 30, 2028. This project grant supports fundamental and translational research investigating how antibody-based therapeutics can modulate G protein-coupled receptor (GPCR) signaling to address critical maternal and fetal...
- Federal Grant Award Summary The University of Rochester received a $415,613 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded February 24, 2026, with completion targeted for January 31, 2028. This research project investigates how pregnancy influences methylmercury (MeHg) metabolism and elimination in pregnant women and their developing fetuses. The research builds upon preliminary evidence...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the Regents of the University of Michigan a $3.13 million Project Grant under the Environmental Health program (CFDA 93.113) on September 10, 2025, with completion anticipated by September 9, 2029. The research initiative, conducted at the University of Michigan's Ann Arbor campus, aims to integrate exposome and epigenome analyses to identify determinants of amyotrophic lateral sclerosis...
- Federal Grant Award Summary The University of Texas Medical Branch at Galveston received a $718,775 Project Grant from the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113) to conduct research on understanding the role of gut microbiome in trichloroethene (TCE)-mediated autoimmunity. The award, obligated on April 1, 2026, with a completion date of January 31, 2031, will fund mechanistic research investigating how environmental TCE exposure...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $163,856 Project Grant to the University of New England on April 10, 2026, under the Environmental Health program (CFDA 93.113). This award supports a prospective epidemiological study investigating the association between per- and polyfluoroalkyl substance (PFAS) mixtures and adverse pregnancy outcomes in a cohort of reproductive-aged Black women from Detroit, Michigan. The research...
- Federal Grant Award Summary The University of Michigan, through its Office of Research and Sponsored Projects, received a $780,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective August 1, 2025, through July 31, 2028. The funded research project, "Lead Exposure and Sex-Specific Programming of Cardiovascular Disease Across the Life Course," will be conducted at the University of Michigan's Ann...
- Federal Project Grant Award Summary Duke University received a $3.12M Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 5, 2025, with completion targeted for September 4, 2029. The research initiative investigates the mechanisms by which per- and polyfluoroalkyl substances (PFAS) exposure impairs placental function and fetal development through disruption of mitochondrial function and...
The University of Michigan has received a $795,869 Project Grant from the National Institute of Environmental Health Sciences under the Environmental Health program (CFDA 93.113), awarded on April 16, 2026, with completion targeted for February 28, 2031. This research initiative investigates how volatile organic compounds (VOCs), specifically trichloroethylene (TCE) and perchloroethylene (PCE), impair immune functions during pregnancy through molecular mechanisms. The project will deliver foundational research examining how TCE and its metabolite S-(1,2-dichlorovinyl)-L-cysteine (DCVC) suppress immune responses in gestational tissues, including the uterus, fetal membranes, and placenta, with particular focus on immune defenses against bacterial pathogens such as Group B Streptococcus. The research will produce scientific knowledge regarding environmental toxicant impacts on pregnancy health outcomes and generate evidence to support the design of targeted interventions to prevent adverse pregnancy complications, including preterm birth, stillbirth, neonatal sepsis, and fetal growth restriction. By identifying the molecular pathways through which VOC exposure disrupts immune cell function and cytokine release, this project contributes to the NIEHS mission of translating environmental health research into strategies that reduce disease burden and promote population health, with particular relevance to vulnerable pregnant populations exposed to environmental contaminants in water and air.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $795.9k | 4/17/26 |