Project Grant R01ES036951
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health federal grant program (CFDA 93.113), provides $546,350 to fund a study to "Define the Neurotoxic and Neurodevelopmental Health Risks of Per- and Polyfluoroalkyl Substances (PFAS)". The key objectives of this 4.5-year research project are to: 1) Characterize the mechanisms by which PFAS facilitate neuronal uptake and accumulation; 2) Elucidate the...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $695,853 to the Arkansas Children's Research Institute (ACRI) from December 1, 2024 to November 30, 2029. The project will investigate the impact of prenatal and postnatal exposure to per- and polyfluoroalkyl substances (PFAS) on children's development, examining the role of placental function and the potential protective...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), will support research at Brown University to investigate the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on adult cardiometabolic disease. The $656,250 award, with a performance period from August 6, 2025 to May 31, 2029, will enable researchers to conduct an unprecedented assessment of 44 individual PFAS,...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $121,057 to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct a prospective study investigating associations between per- and polyfluoroalkyl substance (PFAS) mixtures and pregnancy outcomes among Black women. The research aims to: 1) evaluate the association of a PFAS mixture with adverse...
- This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $561,584 to Rutgers, The State University of New Jersey to study the ovarian disrupting effects of per- and polyfluoroalkyl substances (PFAS) on female reproductive health. The research aims to elucidate the mechanisms by which PFAS exposure, particularly perfluorononanoic acid (PFNA), interferes with ovarian...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a Project Grant of $157,500.00 to the Regents of the University of California at Riverside (UC Riverside) to pilot a study on developmental exposure to per- and polyfluoroalkyl substances (PFAS) and its potential interactions with genetic factors that may contribute to the risk of autism spectrum disorder (ASD). The study aims to investigate how...
- The National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), awarded a $143,331 Project Grant to Wayne State University to investigate the molecular impacts of per- and polyfluoroalkyl substances (PFAS) exposure on male reproductive health. The research aims to use single-cell RNA sequencing and analysis of epididymal extracellular vesicles to decipher how PFAS exposure affects spermatogenesis, sperm epigenetics, and overall...
- This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health Federal Grant Program (CFDA 93.113), is supporting research to investigate the long-term metabolic, vascular, and bone health effects of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) mixtures. The $463,850 award to Brown University will leverage the New England Family Study (NEFS) cohort to measure PFAS concentrations in stored pregnancy and...
- This $478,503 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) supports research to investigate the impact of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on the development of non-alcoholic fatty liver disease (NAFLD) in children. The award will leverage the existing GUSTO mother-child cohort in Singapore to conduct comprehensive assessments, including proton magnetic resonance...
- This $701,121 federal Project Grant award from the Department of Defense's Defense Health Agency, issued under the Military Medical Research and Development program (CFDA 12.420), supports research on the ovarian-disrupting effects and mechanisms of per- and polyfluoroalkyl substances (PFAS). The project is being conducted by Rutgers, The State University of New Jersey's RBHS-School of Nursing over a 3-year period from September 2023 to September 2026. The research aims to develop a better...
This Project Grant award, valued at $3,121,590.00 and funded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113), supports research conducted by Duke University to investigate the impacts of per- and polyfluoroalkyl substances (PFAS) exposure on placental function and fetal development. The key objectives of the research are to: 1) examine mitochondrial perturbations associated with PFBS (an emerging PFAS compound) exposure in human placental trophoblast cells; 2) determine which specific mitochondria-relevant syncytiotrophoblast functions are altered by PFBS exposure; and 3) assess alterations in placental hemodynamics, oxygenation, and mitochondria-relevant metabolism caused by PFBS and PFAS mixtures in mice. This work aims to advance the understanding of how widespread PFAS contamination can disrupt reproductive health through mitochondrial dysfunction and metabolic changes in the placenta and fetus.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $3.1m | 9/4/25 |