This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $728,029 to Emory University to conduct a cross-sectional study on the role of gut microbiota, inflammation, and metabolomics in heat-related illness (HRI). The project, titled "GIRASOLES 2.0: UNDERSTANDING THE ROLE OF MICROBIOTA, INFLAMMATION, AND METABOLOMICS IN HEAT-RELATED ILLNESS", aims to evaluate how gut microbial communities, systemic and gut inflammation, short-chain fatty acids, and bile acids influence the likelihood and severity of HRI in 100 agricultural workers exposed to extreme heat environments. The study will utilize whole genome sequencing, inflammatory biomarker analysis, and metabolomics to improve understanding of the interrelationships between these factors and inform the development of novel HRI biomarkers and prevention/treatment approaches. The project period runs from January 1, 2025 to December 31, 2027.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $728.0k | 12/20/24 |