Project Grant R01EB038047
Award Date 8/15/25
Completion Date 5/31/29
Dollars Obligated $528K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
South Carolina, USA
Similar Awards
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) provides $288,428 in funding to The Washington University to conduct collaborative fundamental research on developing a new type of antimicrobial nanoparticle to combat antibiotic-resistant bacteria. The project aims to elucidate how the non-uniform surface chemistry of these specialized nanoparticles interacts with bacterial cell walls to achieve novel antimicrobial mechanisms that are less...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $593,860 Project Grant through the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Massachusetts (UMass) for the development of new polymer-phage conjugate nanoparticles to treat antibiotic-resistant wound biofilm infections. The 5-year project, which began on June 6, 2025, seeks to create phage-polymer nanoparticles that can effectively penetrate and eradicate biofilm infections...
- This $392,634 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports the development of a novel nanoimmunotherapeutic approach to combat multidrug-resistant (MDR) bacterial infections. The project aims to design, fabricate, and optimize a red blood cell membrane-coated, hemoglobin-encapsulating nanoparticle (RHNP) that can sensitize bacteria to host oxidant killing while...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $474,363.00 to Rowan University to develop novel antimicrobial peptides inspired by the clinically approved compound daptomycin. The goal is to create new peptide molecules that mimic daptomycin's key mechanisms of action, such as calcium binding and lipid membrane disruption, while improving resistance to...
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $821,426 Project Grant on January 16, 2025 under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the University of Nebraska Medical Center. The grant supports the development of nanostructures that are selectively targeted to bacteria, with a focus on two pathogens of particular concern: Staphylococcus aureus and Acinetobacter baumannii. The...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $569,210 to the University of Colorado Boulder to conduct research on the "Mechanisms of Lipid A Modification Impacting Antimicrobial Resistance". The key focus is on understanding how certain gram-negative pathogens modify their lipid A structures to develop resistance against cationic antimicrobial...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $416,050 to The Washington University in University City, Missouri to conduct research on understanding the metabolic and regulatory control of antibiotic production in filamentous actinobacteria. The research aims to investigate two families of antibiotic molecules - polycyclic tetramate macrolactams and...
- This federal Project Grant award of $442,710, awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), is focused on characterizing novel lanthipeptide natural products from marine bacteria. The objective is to structurally elucidate the lanthipeptide compounds produced by two biosynthetic gene clusters identified in an ecologically important marine bacterial species, test their antibiotic potential against...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $195,625 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to the University of Colorado Boulder. The grant supports research to structurally and functionally characterize phosphoethanolamine (PEtN) transferases, enzymes responsible for conferring resistance to cationic antimicrobial peptides (CAMPs) and the antibiotic colistin in multidrug-resistant Gram-negative...
- This $475,036 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will fund research to explore synergistic combinations of aminoglycoside antibiotics against multidrug-resistant (MDR) gram-negative bacteria. The project aims to: 1) examine dual-aminoglycoside combinations against MDR pathogens like Enterobacter cloacae, E. coli, and Klebsiella pneumoniae, 2) solve the structural details of how multiple...