Project Grant R01EB036942

Award Date 1/1/25
Completion Date 12/31/28
Dollars Obligated $477K
Federal Grant Program
93.286
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
This $384,863 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program supports research to develop a novel radiotracer imaging agent for detecting Gram-positive bacterial infections associated with implanted medical devices. The key products and services to be delivered include: In vitro testing of a bivalent radiotracer agent...
This Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $554,188 to The Trustees of the University of Pennsylvania to develop silver telluride nanoparticle contrast agents for use in dual-energy mammography screening for breast cancer. The award will fund several key activities to advance these novel contrast agents towards clinical translation, including: Adapting the nanoparticle synthesis process for scalable production...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $185,171 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to The Johns Hopkins University to develop and optimize polymeric chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) agents. The research aims to enhance the sensitivity and specificity of these molecular MRI agents for detecting prostate conditions, including benign...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $359,995 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to Clemson University. The funding supports the development and validation of a novel X-ray visualized immunosensor (X-VIS) that can be attached to implanted medical devices to detect and monitor local infection biomarkers. The project aims to fabricate a...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports the development of novel radiofluorination methods for rapidly accessing positron emission tomography (PET) imaging agents. The $505,848.59 award, spanning from September 1, 2024 to August 31, 2027, will fund research by the University of Pennsylvania to...
This National Science Foundation (NSF) Project Grant, awarded under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), provides $168,690 to the Florida Institute of Technology Inc. (Florida TECH) to develop a theragnostic (therapeutic + diagnostic) system for inflammatory bowel diseases (IBD). The project aims to model the complex interplay of host, microbial, and environmental factors that trigger IBD using data science, and then leverage synthetic biology and...
This $202,728 federal Project Grant awarded by the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program funds a collaborative research project to develop a theragnostic (therapeutic and diagnostic) system for inflammatory bowel diseases (IBD). The project aims to integrate data science, synthetic biology, and additive manufacturing to model the complex interplay of host, microbial, and environmental factors in IBD, and develop an engineered...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $709,094 Project Grant (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) to The Johns Hopkins University to research "Pixelated Scintillators for Ultra-High Resolution Cone-Beam CT". The project aims to advance the development of indirect-detection X-ray flat panel detectors used in medical imaging, by improving the performance of scintillator materials...
This National Cancer Institute (NCI) Project Grant Award under the Cancer Detection and Diagnosis Research program (CFDA 93.394) provides $666,670 to The Trustees of the University of Pennsylvania (Penn) from January 15, 2025 to December 31, 2028. The goal of this project is to develop methods and protocols to obtain high-quality dynamic information from both PET and spectral CT imaging modalities, and use dynamic spectral CT for PET kinetic modeling to reduce overall scan time to match existing...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), focuses on developing advanced MRI techniques to enable faster, more robust pediatric imaging without the need for anesthesia or contrast agents. The $1,806,252 award to The Leland Stanford Junior University aims to create MRI protocols that can rapidly image the bowel...

This federal Project Grant award of $477,129 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) supports the development and testing of a novel computed tomography (CT) contrast agent, dextran-coated cerium oxide nanoparticles (DEX-CENP), for imaging inflammatory bowel disease (IBD). The project aims to characterize several variations of DEX-CENP, evaluate their potential for CT imaging of IBD, and assess their therapeutic efficacy for treating IBD. Key deliverables include demonstrating the DEX-CENP's ability to produce strong CT contrast and accumulate in IBD-affected areas of the large intestine, as well as evaluating the safety and anti-inflammatory properties of the nanoparticles. The 4-year project, beginning January 1, 2025, is being conducted by the Trustees of the University of Pennsylvania.

Generated 7/1/25, 2:50 AM