Federal Project Grant Award Summary

The Leland Stanford Junior University received a $782,886 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective February 18, 2026, through January 31, 2031. The research initiative focuses on controlling obesity through development and investigation of an appetite-suppressing peptide as a therapeutic intervention for metabolic disorders. This project addresses a critical public health need, as obesity is associated with a 5–10 year decrease in life expectancy and increased mortality from diabetes and cardiovascular diseases.

The award supports basic and translational research activities at Stanford's facilities in Stanford, California, aimed at advancing scientific understanding of peptide hormone mechanisms relevant to obesity and metabolic disease treatment. As part of the NIDDK's broader extramural research portfolio, this project grant will contribute to the development of improved preventions, diagnoses, and treatments for obesity and related metabolic conditions through investigator-initiated research conducted over the five-year performance period.