This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is providing $720,850 to Harvard Pilgrim Health Care Inc. to conduct research on improving the validity of linked real-world data studies for diabetes mellitus research. The key objectives are to: 1) develop systematic approaches to investigate potential biases in using linked real-world data sources for comparative effectiveness and safety research of glucose-lowering treatments, 2) develop and evaluate design and analytic methods to maximize internal validity of such studies, and 3) apply novel generalizability and transportability techniques to improve the external validity and extend the findings to target populations. This 4-year project, starting in March 2025, aims to help diabetes researchers maximize the potential of linked real-world data and generate robust real-world evidence to complement randomized controlled trials.
Generated 3/25/25, 4:21 AM