This Project Grant award, with the ID R01DK138518, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $621,812 funding will support research at Baylor College of Medicine to examine the neural circuits regulating feeding behavior and body weight control, with a focus on the role of cholinergic neurocircuitry in the ventral subiculum and its downstream outputs. The research aims to systematically dissect the neural pathways mediating the anorexigenic effects of ventral subiculum neurons, explore the physiological relevance of this circuit in chronic feeding and weight regulation, and elucidate the role of nicotinic acetylcholine receptor signaling within the ventral subiculum in suppressing feeding behavior. The award period runs from June 1, 2024 to April 30, 2028.
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