The Children's Hospital Corporation, doing business as Boston Children's Hospital, received a $663,173 project grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) through the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to better understand how butyrate, a gut-derived metabolite, impacts the composition and function of Bacteroides bacteria in the gut microbiome. The research aims to leverage glycan-butyrate interactions to shape beneficial Bacteroides communities and optimize butyrate levels for improved gut and overall health. The findings are expected to advance knowledge of microbial ecology, diet-microbe-host interactions, and colonic health, with potential translational applications. The project period runs from July 2024 to April 2028.
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