The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,543,110 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to New York University (NYU) School of Medicine. The objective is to better understand how the gut microbiome and related host factors influence urinary oxalate levels, which can contribute to kidney stone formation and chronic kidney disease. The 4-year research project will leverage NYU's access to data and samples from large cohorts to investigate the role of the "oxalobiome" in oxalate metabolism, as well as the interplay between the gut microbiome, host genetics, and other factors in determining urinary oxalate excretion. The project aims to reveal therapeutic approaches for managing the adverse effects of elevated oxalate levels.
Generated 3/4/25, 6:29 AM