This $650,450 Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) supports the development of a novel TCR-engineered CD4+ T cell therapy for the treatment of lung cancer. The funded research project, led by the University of Southern California, aims to: The overall goal is to advance the development of this TCR-T cell immunotherapy for lung cancer patients, and potentially expand its application to other cancers expressing the CT83 antigen. The project builds upon previous research demonstrating the robust anti-tumor activity of the MIIC4 TCRM50A-STEM2 T cells in preclinical models.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $650.5k | 6/9/25 |