This Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) provides $536,836 to The University of Texas MD Anderson Cancer Center to address open issues related to transient multiphase flow and heat transfer in biological tissues. The research will develop mathematical models to understand the thermal, hypoxic, and pH response of a thermoembolization therapeutic approach for treating hepatocellular carcinoma. The validated models will be used to optimize delivery protocols and provide fundamental understanding of the mechanisms that define successful treatment. This 5-year project runs from March 2025 to February 2030 and involves a multidisciplinary team of experts in imaging physics, mathematical modeling, numerical algorithms, interventional radiology, and biochemistry.
Generated 4/1/25, 3:30 AM