The National Cancer Institute (NCI) awarded a $657,844 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to The Medical College of Wisconsin, Inc. (MCW) to examine the efficacy of a 16-week lifestyle intervention on physical function and patient-reported outcomes among 184 individuals with stable multiple myeloma. The study, titled "Moving Forward with Multiple Myeloma," will also explore associations between lifestyle behaviors and prognostic biomarkers related to metabolic health, inflammation, and cellular senescence. This grant award, effective March 10, 2025, represents a critical step in understanding how lifestyle interventions can benefit multiple myeloma survivors as they manage the chronic burdens of their cancer and related treatments over the 5-year project period ending February 28, 2030.