Project Grant R01CA292529
- The University of Michigan has been awarded a $568,151 Project Grant from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) to develop a real-time functional imaging platform for accurate diagnosis and prognosis of prostate cancer. The project aims to leverage photoacoustic imaging and biocompatible hydrogel nanoparticle probes to quantitatively assess prostate gland microarchitecture and tumor microenvironment as imaging biomarkers for improved prostate...
- The University of Chicago received a $372,628 Project Grant from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) on September 12, 2025. The grant funds the development of a large-format spatial transcriptomics profiling platform, called Array-Seq, to enable detailed spatiomolecular analysis of human cancer samples. This technology aims to overcome limitations of existing spatial transcriptomics methods by increasing throughput, sample size compatibility, and...
- This federal Project Grant award, valued at $682,272.00, was provided by the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research (CFDA 93.393) program. The award will fund a research project entitled "Assessing Feasibility and Acceptability of a Multifaceted EHR-Integrated Mobile Health Intervention Following Radical Cystectomy" at the University of Michigan. The goal of the project is to develop and evaluate a novel, technology-enabled intervention to reduce...
- The University of Michigan received a $136,412 Project Grant award from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower program) to conduct research on defining and interrupting metabolic processes that support glioblastoma, an aggressive form of brain cancer. The goal of the 2-year project is to determine how glioblastoma tumors co-opt brain-derived metabolites like glutamine and lactate to fuel tumor growth and therapy resistance. The research will use in vitro models to...
- This $462,153 Project Grant was awarded on September 4, 2025 by the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) to Northern Michigan University (NMU). The grant will fund the development and utilization of a novel genetically encoded fluorescent biosensor, D2HGLO, to quantify intracellular concentrations of the oncometabolite d-2-hydroxyglutarate (d-2-HG) in cancer cells. This innovative tool will allow researchers to study the subcellular localization and...
- This $576,493.00 federal Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) aims to develop sophisticated, self-calibrating near-infrared fluorescent probes that can quantitatively assess microviscosity variations and monitor protein misfolding/aggregation within live cells. The probes are designed to have enhanced water solubility, stability, and cell permeability to maximize biocompatibility and selectivity for detecting viscosity changes and protein...
- This $1,248,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program will support the "RARE-CANCER COMMONS: A HUB FOR ACCELERATING INDIVIDUALIZED RARE CANCER THERAPY THROUGH INTEGRATION OF SINGLE-CELL AND CLINICAL GENOMICS DATA" research initiative at the University of Michigan. The project, running from November 1, 2024 to October 31, 2027, will leverage the University's extensive research capabilities to...
- The National Cancer Institute (NCI) awarded a $591,468 Project Grant on August 6, 2025 under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to The Research Foundation for the State University of New York (SUNY Oswego). The funding supports research to develop explainable machine learning models based on deep cancer pathophysiology to improve cancer diagnosis, risk stratification, and therapeutic recommendations. The project aims to address key gaps in integrating heterogeneous...
- The National Cancer Institute (NCI), part of the U.S. Department of Health and Human Services, awarded a $677,998 Project Grant under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to The Medical College of Wisconsin, Inc. (MCW). The project aims to externally validate and integrate radiopathomic models developed using autopsy and biopsy samples to better delineate the true extent of glioma tumors and identify microscopic infiltrating tumor cells. The research will refine...
- The University of Michigan will receive $1.2 million from the Defense Health Agency under a three-year Project Grant award for research titled "FADD: A Mechanistic Basis and Therapeutic Opportunity for Overcoming CDK4/6 Inhibitor Resistance." The grant is part of the Military Medical Research and Development program (CFDA 12.420), which supports basic, applied, and advanced biomedical research to transform military and public health care through innovative medical solutions for...
The University of Michigan was awarded a $2,284,054 Project Grant by the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research (CFDA 93.394) federal grant program. The 4-year grant, which began on September 1, 2025, will support research to transform molecular cancer screening through the development of stimulated Raman histology and deep neural networks. The project aims to improve access to molecular cancer testing by creating innovative diagnostic tools and methods that overcome current infrastructure and logistical barriers. The research will focus on advancing early cancer detection, risk assessment, and treatment monitoring capabilities through the application of emerging technologies such as artificial intelligence, liquid biopsy, and biomarker discovery.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.3m | 9/8/25 |