The Leland Stanford Junior University (Stanford University) has been awarded a Project Grant of $648,428.00 from the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research program (CFDA 93.394). The funding will support research to identify tumor microenvironmental biomarkers that drive the transition from ductal carcinoma in situ (DCIS) to invasive breast cancer.
The project aims to utilize in vivo analyses, in vitro studies, and computational modeling to determine which changes in the extracellular matrix, macrophage activity, and fibroblast signaling are causally linked to the DCIS to invasive breast cancer transition. The research findings are expected to improve prognostic indicators for DCIS patients and help detect the presence of unsampled invasive cancer. The award period runs from December 13, 2024 to November 30, 2029.
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