This Project Grant award from the National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), is for a research project titled "Single-Scan, Multi-Contrast Imaging of Glucose Metabolism in Patients with Glioblastoma." The $677,801 award, effective January 2, 2025 through December 31, 2029, will fund research at Yale University to develop a magnetic resonance imaging (MRI)-based metabolic imaging technique called Deuterium Metabolic Imaging (DMI) to quickly characterize disease progression in glioblastoma, the most aggressive form of brain cancer. The project aims to validate the specificity of DMI for detecting active tumor, establish the repeatability of glucose DMI measurements, and demonstrate the use of DMI to detect true disease progression in a clinical setting. Successful completion of these aims could establish DMI as a robust, non-invasive metabolic imaging method that can be integrated into standard MRI protocols to improve glioblastoma management.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $677.8k | 1/2/25 |