The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania, received a $312,627 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The purpose of this 4-year grant, which runs from December 2024 to November 2028, is to establish orbital and cranial vessel wall magnetic resonance imaging (OVW-MRI) as an imaging biomarker for assessing disease activity in giant cell arteritis, including ocular involvement. The research aims to validate OVW-MRI as a diagnostic tool and determine its responsiveness and convergent validity in monitoring disease progression and treatment effectiveness. This work will help address the critical need for objective measures of disease activity in giant cell arteritis to support treatment decision-making and clinical trials.
Generated 3/4/25, 7:43 AM