The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $718,693 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) to a partnership between Henry Ford Health and Michigan State University Health Sciences. This funding will support a 5-year research project (9/18/2024 - 8/31/2029) to conduct whole-genome sequencing analysis of Hidradenitis Suppurativa (HS), a debilitating inflammatory skin disorder. The project aims to identify genetic factors contributing to racial and sex disparities in HS risk and severity, and uncover functionally relevant genetic variants that could lead to new therapeutic targets. The researchers will leverage their unique patient cohorts as well as the All of Us Research Program's whole-genome sequencing data to perform genetic association analyses. This work will provide insights into the genetic underpinnings of HS and pave the way for developing improved diagnostic, preventive, and treatment strategies for this complex skin condition.
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