This $428,357 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) aims to develop an implantable "osseosurface electronics" device for real-time monitoring of bone health in rodent models. The device will leverage wireless, battery-free sensors that integrate with bone tissue to capture strain and thermal conductivity data. This data will be used to evaluate the sensitivity of the device in detecting bone changes compared to standard techniques like dual-energy X-ray absorptiometry (DEXA) and micro-computed tomography (MCT). The research conducted under this 5-year grant will help expand the capabilities of this novel implantable sensor platform and assess its potential utility for chronic monitoring and treatment of osteoporosis in patient populations.
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