Project Grant R01AI195271
- Federal Project Grant Award Summary Georgia TECH Research Corp received a $390,942 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 12, 2025, with a completion date of May 31, 2030. The project focuses on developing self-assembled peptide nanoparticles (SAPNs) as a universal influenza vaccine platform. The primary deliverable is the design, evaluation, and enhancement of...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded J. David Gladstone Institutes a Project Grant of $3.56M under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop an innovative hybrid messenger RNA (mRNA) vaccine technology for HIV-1. The award, obligated on September 26, 2025, with a completion date of August 31, 2029, supports research into a novel vaccine platform that combines features of both mRNA and protein...
- Federal Grant Award Summary Georgia State University Research Foundation Inc. received a $660,334 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 24, 2025, with a completion date of August 31, 2030. The award supports research and development of an innovative outer membrane vesicle (OMV)-based vaccine targeting Neisseria gonorrhoeae, the causative agent of gonorrhea....
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $791,661 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2030. The award funds research to develop and evaluate an integrase-defective lentiviral vector (IDLV) vaccine platform designed to deliver HIV-1 gag and membrane-tethered envelope trimers as a...
- Federal Grant Award Summary The Scripps Research Institute received a $910,905 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 1, 2025, with completion targeted for June 30, 2026. The project delivers research and development services focused on advancing HIV vaccine development through a lipid nanodisc platform technology. Specifically, the research incorporates engineered...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $208,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2028. The award funds research and development of a multivalent messenger RNA (mRNA) HIV vaccine designed to elicit broadly neutralizing antibodies (BNAbs) targeting conserved epitopes on HIV...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $3,017,032 to Scripps Research Institute on August 8, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to design single-shot sequential immunization regimens for HIV using atomic layer deposition (ALD) technology. The project, which extends through July 31, 2029, focuses on developing vaccine formulations capable of delivering multiple booster...
- Federal Project Grant Award Summary The Scripps Research Institute received a $1,379,954 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 21, 2025, with a completion date of July 31, 2030. The award supports systematic research to advance HIV vaccine development by engineering durable immunity through optimization of vaccine parameters. The research deliverables...
- Federal Grant Award Summary Emory University received $653,693 in project grant funding from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a one-year project period from May 12, 2025, through April 30, 2026. The award supports structural research on HIV-1 virion assembly and maturation mechanisms, with particular focus on understanding how the capsid-targeting antiviral compound lenacapavir...
- Federal Project Grant Award Summary The University of Florida, through its Division of Sponsored Research, received a Project Grant of $1,016,887 awarded on August 6, 2025, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research extending through July 31, 2030, and is being performed in Jupiter, Florida. The project focuses on the discovery and development of novel HIV-1 TAT...
Georgia Tech Research Corp received a $725,241 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 2, 2026, through January 31, 2031. The award supports research and development of controlled-delivery HIV-1 vaccines utilizing advanced immunological and chemical platforms. The project delivers integrated research products encompassing: (1) tunable injectable hydrogels providing extended-release vaccine immunogen delivery; (2) virus-like particle platforms for multivalent antigen presentation; (3) state-of-the-art SOSIP-based envelope glycoprotein immunogens focused on the HIV-1 fusion peptide; and (4) nanoparticle-formulated TLR7/8 adjuvant delivery systems designed to enhance vaccine efficacy. The research initiative combines innovative chemistry, immunogen display strategies, and delivery mechanisms to generate durable and protective HIV-1-specific immunity. The research team will conduct comprehensive vaccine development studies in non-human primates, evaluating immune responses at the cellular, molecular, and antibody-epitope levels to optimize clinical translation potential. The work represents a multidisciplinary effort to advance vaccine-induced immunological responses through prolonged antigen and adjuvant delivery systems, with the ultimate objective of establishing safe and effective HIV-1 vaccine candidates suitable for human clinical development.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $725.2k | 1/28/26 |