Project Grant R01AI191514
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $661,313 Project Grant (R01) to Massachusetts General Hospital effective February 6, 2026, through January 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research focuses on developing a universal influenza vaccine by eliciting pan-influenza A broadly neutralizing antibodies (BNAbs) through engineered nanoparticle immunogens. The investigation...
- Federal Project Grant Award Summary Georgia TECH Research Corp received a $390,942 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 12, 2025, with a completion date of May 31, 2030. The project focuses on the research and development of self-assembled peptide nanoparticles (SAPNs) as a universal influenza vaccine platform. The research effort addresses the limitation...
- Federal Grant Award Summary The University of California, Irvine received a $721,365 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026 through March 31, 2031. This award supports research and development of an innovative single-dose influenza vaccine platform designed to overcome limitations posed by viral antigenic drift. The research combines nanoparticle-based...
- The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $649,455 Project Grant to the Board of Regents of the University of Nebraska on April 15, 2025. The grant is funded through NIFA's Agriculture and Food Research Initiative (CFDA 10.310) and supports a 3-year project to develop vaccines for the prevention of swine influenza pandemics. The University of Nebraska, a comprehensive research institution, will leverage its expertise in agriculture,...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $436,157 to the Board of Regents of the University of Nebraska (University of Nebraska Medical Center) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on April 6, 2026, with a completion date of March 31, 2028. This Project Grant funds research to reassess West Nile Virus (WNV) action thresholds for improved disease control. The project will evaluate how the...
- This Project Grant award of $649,943.00 from the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) supports the development and updating of vaccines against influenza A virus of swine. The University of Nebraska is the primary awardee and will leverage its multidisciplinary expertise in agricultural research, technology innovation, and vaccine development to deliver this versatile, non-infectious vaccine platform. The project aims to...
- Federal Project Grant Award Summary Award Details: The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $676,666 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Massachusetts General Hospital, effective September 3, 2025 through August 31, 2030. The award supports research to develop an enhanced influenza messenger RNA (mRNA) vaccine utilizing a self-amplifying mRNA (saRNA) formulation delivered via microneedle patch technology....
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Viva Viral Vaccines, Inc. a Project Grant totaling $299,968 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period of September 25, 2025 through August 31, 2026. The award supports development of a broad-spectrum, multivalent vaccine platform targeting influenza neuraminidase (NA) protein to provide enhanced protection against seasonal and pandemic...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Alabama at Birmingham a $587,885 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 18, 2025, with a completion date of August 31, 2030. This research project focuses on defining the structure-function relationships that regulate influenza virus non-structural protein 1 (NS1) and nuclear export protein (NEP), two viral...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the Regents of the University of Minnesota $720,588 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 1, 2025, for a five-year project period extending through July 31, 2030. This Project Grant supports the development of broadly protective vaccines against New World arenaviruses, which cause severe hemorrhagic fevers and other serious diseases in...
The Board of Regents of the University of Nebraska received a $799,792 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 1, 2026, with a completion date of March 31, 2031. The project focuses on developing a universal influenza vaccine designed to provide broad, long-lasting protection against divergent influenza virus strains. The research combines multiple vaccine development strategies, integrating immunodominant hemagglutinin 1 (HA1) head domains derived from computationally-optimized epigraph vaccine approaches with conserved hemagglutinin 2 (HA2) stalk domains from consensus immunogens to create novel combination immunogens superior to existing monovalent and commercial vaccine approaches. The project builds upon previously validated preclinical findings demonstrating enhanced cross-protective immunity in mice, ferrets, and swine models. Research activities will be conducted at the University of Nebraska's Lincoln campus and will employ multiple vaccine delivery platforms, including recombinant proteins, viral vectors, and messenger RNA-lipid nanoparticles (mRNA-LNPs). The deliverable is a scientifically validated, combination-based universal influenza vaccine immunogen with demonstrated potential for improved breadth of protection against pandemic influenza virus variants compared to existing vaccination strategies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $799.8k | 4/1/26 |