The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $749,594 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Research Foundation For The State University Of New York, doing business as Stony Brook University. The grant, which runs from Feb 1, 2025 to Jan 31, 2030, supports research on the role of the host sphingosine kinase 1 (SK1) pathway in controlling infection by the fungus Cryptococcus neoformans during immunodeficiency. Specifically, the project aims to: 1) determine the immune mechanism by which the SK1-S1P pathway regulates the organization of Cryptococcus granulomas, and 2) define the immune response by which the SK1-S1P pathway protects against Cryptococcosis reactivation. The research leverages Stony Brook's expertise in biomedical sciences and infectious disease research to advance scientific understanding in this area with potential public health implications.
Generated 3/4/25, 2:10 AM