Project Grant R01AG092507
- This Project Grant award for $500,000 was provided by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to support the development of a novel imaging platform for early detection of Alzheimer's disease (AD). The project, titled "Imaging of Neurovascular Response for Assessment of Alzheimer's Disease," aims to enable rapid, non-invasive assessment of cerebrovascular dysfunction associated with AD by estimating localized neurovascular reactivity in...
- This Project Grant award from the National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), is funding the development of an eyedrop diagnostic test for Alzheimer's disease (AD). The total award amount is $493,384 and the performance period is from September 20, 2025 to September 19, 2026. The goal is to optimize a fluorescent dye that can label pathological protein aggregates in the eye and be imaged using standard ophthalmology equipment, providing a...
- The National Institute on Aging (NIA), under the Federal Aging Research program (CFDA 93.866), awarded a $245,148 project grant to Eyenexo LLC to develop an automated rodent behavior testing system for non-invasively assessing early-stage Alzheimer's disease (AD). The project aims to develop a behavior biomarker that can differentiate AD from normal aging by studying defensive behaviors triggered by looming stimuli, which are linked to early AD pathology in the midbrain region. The 2-year...
- The National Institute on Aging (NIA), through the Aging Research Federal Grant Program (CFDA 93.866), awarded a $495,731 project grant to Viewmind Inc. on September 20, 2025. The project aims to evaluate Viewmind's ability to use machine learning, virtual reality, and eye-tracking technology to detect beta-amyloid and tau burden consistent with Alzheimer's disease in individuals with mild cognitive impairment. The goal is to develop a non-invasive, cost-effective, and rapid diagnostic tool that...
- The National Institute on Aging (NIA) awarded a $1,783,700.00 Project Grant under the Aging Research program (CFDA 93.866) to the University of Illinois to develop novel blood-brain barrier permeable multimodal imaging agents for the diagnosis of neurodegenerative diseases, with a focus on Alzheimer's disease and related dementias. The 3-year grant aims to employ organic and inorganic chemical design principles to generate diagnostic agents capable of detecting protein aggregation,...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $162,486 project grant to The Research Foundation For The State University Of New York (operating as Upstate Medical Center) on January 24, 2025. The project aims to enhance understanding of the biological signatures that distinguish subgroups of Alzheimer's disease (AD) patients using state-of-the-art computational approaches to jointly analyze genetic, epigenetic, and neuroimaging...
- The National Institute on Aging awarded a $4.6 million Project Grant to Cornell University under the Aging Research program (CFDA 93.866) to develop new imaging techniques for measuring microvascular blood flow in Alzheimer's disease and related dementia models. The award will support the design of an adaptive excitation source for 2-photon and 3-photon fluorescence microscopy to simultaneously measure blood flow speeds in approximately 300 cortical or 50 deep white matter microvessels. This...
- The National Institute on Aging (NIA) awarded a $6,925,230 Project Grant under CFDA 93.866 (Aging Research) to The Trustees of Columbia University in the City of New York, effective August 1, 2025 and running through July 31, 2029. The grant funds a research project aimed at developing a "Multi-Organ Chart of Personalized Susceptibility to Alzheimer's Disease and Aging" using large-scale multi-omics and multi-organ biomedical data, advanced AI/ML, and computational genomics statistical...
- This Project Grant award of $108,512.00 was provided by the National Institute on Aging (CFDA 93.866 - Aging Research) to Oregon Health & Science University (OHSU) on March 6, 2025. The goal of this project is to study the mechanisms underlying neurovascular coupling (NVC) impairment and its contribution to cognitive decline and Alzheimer's disease (AD)-related pathology. Specifically, the researchers will investigate how ischemia-induced increases in the vasoconstrictor endothelin-1...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), has awarded a $2,631,670 project grant to The Washington University to investigate age-related deficits in episodic memory for the content and structure of naturalistic events. The 4-year project, starting September 1, 2025, aims to refine the understanding of the process of episodic memory loss in aging and Alzheimer's disease and its links to brain pathology. The study will assess how aging...
The National Institute on Aging (NIA) awarded a $659,094 project grant to Oregon Health & Science University (OHSU) under the Aging Research federal grant program (CFDA 93.866) to develop a novel noninvasive retinal imaging technique for the early detection of Alzheimer's disease. The project aims to leverage the strong connection between retinal and cerebral pathology to create an imaging tool that can identify early-stage Alzheimer's disease, which is critical as emerging therapies are most effective in the earlier stages of the disease. The project period runs from January 1, 2026 to December 31, 2030. The Aging Research program supports comprehensive scientific investigations focused on understanding the biological, clinical, and social aspects of aging, with a particular emphasis on Alzheimer's disease and related dementias.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $659.1k | 12/31/25 |