Project Grant R01AA031494
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273), awarded a Project Grant of $180,939 to Yale University on September 1, 2025. The grant funding will support a study examining neurobiological threat reactivity as a potential biomarker for the comorbidity of chronic pain and alcohol use disorder (AUD). The project aims to use functional neuroimaging to investigate how the anterior insular cortex circuit function correlates with...
- This $232,316 Project Grant awarded by the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) supports research to investigate the role of a novel dynorphinergic circuit in the central amygdala and its connection to the nucleus accumbens. The research aims to understand how this circuit is modulated by chronic pain and fentanyl abstinence, and how it contributes to binge-like alcohol drinking behavior, pain-related cognitive effects, and reinstatement of...
- This federal Project Grant award of $123,045.00 was provided by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273) grant program. The award supports research to investigate interactions between the alcohol and cannabinoid systems in the context of pain and alcohol use disorder (AUD). The project aims to examine the potential analgesic effects of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, on pain...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $601,129 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (CCLCM). The project, titled "Alcohol and Gut-Brain Axis and the Role of Butyrate on Neuroinflammation and Pain Sensitivity", aims to investigate the relationship between alcohol use disorder, chronic pain, and the gut microbiome, with a focus on the role of...
- This Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under CFDA 93.273 - Alcohol Research Programs, will fund a longitudinal study on alcohol consumption, contexts, and consequences across the transition to legal drinking age in the United States. The University of Missouri System will receive $719,749 to conduct this 5-year study, starting on September 10, 2025. The researchers will use ecological momentary assessment (EMA) to collect self-report,...
- This Project Grant award, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to evaluate the relationship between chronic pain and substance use disorders. The $146,922 award, with a project period from December 6, 2024 to June 30, 2026, will support research at Indiana University to: 1) Estimate general and condition-specific associations between chronic pain conditions and substance use disorders/overdose, and 2)...
- This federal Project Grant award in the amount of $5,057,591 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to conduct a comprehensive, prospective observational study with 2,400 emergency department patients seeking care for acute pain. The study aims to: 1) characterize clinically-informed pain phenotypes, 2)...
- The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $143,784 Project Grant (CFDA 93.273 - Alcohol Research Programs) to Louisiana State University Health Sciences Center New Orleans on July 30, 2024. The grant will support research to investigate the effects of adolescent opioid exposure on alcohol-induced hyperalgesia (increased pain sensitivity) in adult mice. The research aims to test the hypothesis that exposure to opioids during adolescence increases the magnitude of...
- This Project Grant award of $153,000.00, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), will support a 6-month longitudinal study examining the relationships between naturalistic cannabis use, pain perception, and functioning (e.g., pain-related disability, physical activity, sleep) in the daily lives of young adults with chronic pain. The study will use an ecological momentary assessment burst design to capture...
- This $407,812 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 Alcohol Research Programs) will fund a study by the University of Oregon examining the dynamic associations between impulsivity, craving, and co-use of alcohol, cannabis, and nicotine among young adults. The study aims to collect intensive longitudinal data from 250 young adults to investigate how impulsiveness and craving vary between and within different substance use episodes, with a...
This $587,361 federal Project Grant awarded by the National Institute on Alcohol Abuse and Alcoholism (CFDA 93.273 - Alcohol Research Programs) to the University of Colorado-Denver will fund a 5-year research project to investigate the relationship between pain, negative affect, and alcohol use. The project will combine laboratory-based pain induction and ecological momentary assessment (daily text-message surveys) to examine pathways from pain to alcohol use, as well as factors like pain modulatory capacity and impulsivity that may moderate this relationship. The research aims to advance understanding of how physical pain can lead to problematic alcohol use, which has significant public health implications. The project will recruit 225 community adults aged 25-80 to participate in the mixed methods study starting in September 2025 through May 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $587.4k | 9/10/25 |