Project Grant P30AG094848
- This federal Project Grant award in the amount of $124,875.00 was provided by the National Institute on Aging (CFDA 93.866 Aging Research) to Cedars-Sinai Medical Center. The grant supports research by Dr. Larissa Langhi Prata, an Assistant Professor at the Kogod Center on Aging at Mayo Clinic, to investigate the role of senescent cells in the susceptibility of elderly and chronically ill patients to infectious diseases. The research aims to provide insights into the biology of aging and its...
- This $2,591,620 Project Grant was awarded by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) to Cedars-Sinai Medical Center in California. The grant is designed to determine the role of hypothalamic neurons in the progression of physiological decline with age, with a focus on understanding the cellular mechanisms responsible for increased frailty in older adults. Key objectives include elucidating the role of arginine-vasopressin (AVP) neurons...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $627,212 Project Grant under the Aging Research program (CFDA 93.866) to the University of California, Berkeley (UC Berkeley) for the "Costa Rican Longevity and Healthy Aging Study (CRELES): Wave 4" research project. The grant, with a performance period from April 1, 2025 to December 31, 2029, will fund a long-term follow-up survey of over 3,500 Costa Rican adults aged 70 and...
- The National Institute on Aging (NIA), part of the U.S. Department of Health and Human Services, awarded a $1,083,046 Project Grant under the Aging Research program (CFDA 93.866) to The Johns Hopkins University. The grant, running from August 1, 2025 to July 31, 2027, will support the development of novel adeno-associated viruses (AAVs) to selectively manipulate oligodendrocyte precursor cells (OPCs) in the central nervous system. The project aims to test the hypothesis that reactive...
- This Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) is supporting the development of a "Multimodal, Multiscale and Multistage Systems Biology (M3SB) Infrastructure for Precision Medicine in Alzheimer's Disease and Longevity". The $802,034 award aims to conduct multi-modal analyses of genetics, multi-omics data, cross-species protein interactome networks, and human brain-specific functional genomic data to identify...
- The University of Southern California received a $126,042 project grant from the National Institute on Aging (NIA), under the Aging Research Federal Grant Program (CFDA 93.866), to investigate the role of mitochondrial proline catabolism, specifically the ALH-6 gene, in muscle-mitochondrial dynamics and their impact on health and longevity. This research builds upon previous studies in C. elegans that have linked ALH-6 mutations to premature aging, impaired muscle function, and mitochondrial...
- The National Institute on Aging (NIA) awarded a $463,318 Project Grant to the University of Maryland, College Park under the Aging Research federal grant program (CFDA 93.866) with a project period of September 1, 2025 to August 31, 2027. The grant funds the "Center for Seniors Uniting Nationwide to Support Health, Integrated Care, and Economics (SUNSHINE)" which focuses on advancing aging resilience by integrating healthcare systems, public health organizations, social services, and...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $166,488 Project Grant to the University of California, Davis to investigate the role of hypoxia-inducible factor-2a (HIF-2a) signaling in age-induced bone loss. The project aims to identify mechanisms underlying bone deterioration with aging and develop novel therapies to reverse age-related osteoporotic bone loss and improve fracture resistance. The project period runs from December...
- The National Institute on Aging (NIA) awarded a $354,000 Project Grant under the Aging Research program (CFDA 93.866) to Panorama Research Incorporated, a for-profit biotech company in Sunnyvale, CA. The grant supports research to develop a novel therapy for sarcopenia, characterized by age-related loss of skeletal muscle mass, quality, and strength. The proposed therapy is based on the adipokine Isthmin 1 (ISM1), which has been shown to promote protein synthesis and suppress degradation...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $344,164 project grant to Northwestern University to develop "M4: Modules on Advanced Methodology When Modeling Multinational Data." The primary objectives are to: 1) create a training program in large-scale data analysis for the next generation of researchers, 2) instruct trainees on protective behavioral and social factors related to Alzheimer's disease and related dementias...
The National Institute on Aging (NIA) awarded a $1,466,297 Project Grant under the Aging Research federal grant program (CFDA 93.866) to the Cedars-Sinai Medical Center, in collaboration with the University of California Los Angeles (UCLA) and the University of Southern California (USC), to establish the Los Angeles Claude D. Pepper Older Americans Independence Center (LA OAIC). This 5-year grant, effective September 1, 2025, aims to extend human healthspan by accelerating and expanding translational geroscience research. Key objectives include developing advanced gerotherapeutics, expanding the scope of clinical trials in translational geroscience, increasing the research workforce, and promoting the dissemination of geroscience knowledge. The LA OAIC will achieve these goals through a comprehensive structure of specialized cores, including Leadership/Administrative, Pilot/Exploratory Studies, Research Education, Advanced Gerotherapeutics, Clinical Research, and Data Science.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 8/29/25 |