Project Grant P01AI196047
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $192,672 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Leland Stanford Junior University, with a performance period from September 1, 2025, through August 31, 2030. This research initiative will investigate the role of PF bacteriophage in promoting Pseudomonas aeruginosa (PA) pathogenesis during chronic lung infections in individuals with...
- Federal Grant Award Summary Stanford University received a $423,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 25, 2025, with completion targeted for June 30, 2027. This research project investigates antimicrobial peptides and antibiotic diffusion in sputum to address treatment challenges in cystic fibrosis (CF) patients. The research focuses on understanding how...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $160,448 Project Grant to The Leland Stanford Junior University on February 15, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research extending through August 31, 2028. The research will develop covalent activity-based probes (ABPs) targeting bacterial D,D-carboxypeptidases as a novel theranostic tool for imaging and treating bacterial otitis media...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Washington University a Project Grant totaling $427,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 1, 2025, through July 31, 2027. The grant supports research to identify and develop novel anti-biofilm therapeutic agents by exploiting bacteriophage mechanisms that penetrate bacterial biofilm matrices. The research focuses on mining...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $395,692 Project Grant to the University of California, San Diego, effective July 17, 2025, through June 30, 2030, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, "Enhancing Bacteriophage Function with Coevolution and Synthetic Biology," addresses the critical public health challenge of antimicrobial resistance (AMR), which...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $435,379 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Michigan State University, in collaboration with Henry Ford Health, effective February 3, 2026, with completion targeted for January 31, 2028. The award funds research to develop a machine learning-based computational prediction model that identifies effective bacteriophages and...
- Federal Grant Award Summary Award: Therapeutic Potential of Mycobacteriophage LYSB Against Mycobacterium Abscessus Infections The National Institute of Allergy and Infectious Diseases (NIAID) awarded Health Research, Inc.'s Wadsworth Center Division a $1.38 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 18, 2025, with completion targeted for June 30, 2030. This research initiative aims to develop D29 mycobacteriophage lysin (LYSB) as a...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Leland Stanford Junior University a Project Grant of $771,210 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 19, 2026, with a completion date of January 31, 2031. This research initiative will be conducted in Palo Alto, California, and focuses on elucidating the molecular mechanisms by which Salmonella enterica serovar Typhimurium (STM)...
- Federal Grant Award Summary Yale University received a $453,629 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2025, with completion targeted for June 30, 2027. The grant supports development and application of PHAGE-SEQ, a high-throughput technology combining phage display of nanobodies (VHH recognition domains derived from camelid heavy chain-only immunoglobulins)...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $151,040 to The Leland Stanford Junior University on February 25, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated biomedical research addressing infectious diseases, allergic conditions, and immunologic disorders through the project period ending September 17, 2028. The funded research focuses...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1.79M Project Grant to The Leland Stanford Junior University under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2031. The Center for Phage Pharmaceuticals (Phage Pharm) will develop advanced research tools and pharmacologic approaches to optimize bacteriophage (phage) therapy for treating antimicrobial-resistant bacterial infections, particularly Pseudomonas aeruginosa airway infections in patients with cystic fibrosis. The center will address critical knowledge gaps in phage pharmacokinetics and pharmacodynamics (PK/PD) that currently hinder the effective dosing and delivery of phage therapeutics. The award supports two synergistic research projects designed to advance phage therapy development. Project 1 will pioneer nuclear medicine-adapted approaches, including positron emission tomography (PET) imaging of radioisotope-labeled phages and sophisticated analytical methods, to track lytic phage distribution and develop quantitative pharmacokinetic models. Project 2 will establish a novel preclinical model by developing a cystic fibrosis transmembrane conductance regulator-knockout (CFTR−/−) rat model to study respiratory phage therapy pharmacodynamics. These research efforts are intended to optimize phage therapy dosing regimens and advance phage therapy as a reliable adjunct or alternative to antibiotics in cystic fibrosis and other therapeutic settings.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.8m | 3/30/26 |