Project Grant K99AI180358
Award Date
8/1/24
Completion Date
7/31/26
Dollars Obligated
$262K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Stanford, CA 94305, USA
Similar Awards
This $126,174 federal Project Grant awarded on May 29, 2025 by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 Allergy and Infectious Diseases Research program) will support research at the University of California, Davis to investigate the local immune response in bacterial skin infections using a novel skin-on-a-chip model. The overarching goals are to gain mechanistic insights into the migration of hematopoietic stem and progenitor cells (HSPCs) into human skin and...
This Project Grant award of $141,609 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to investigate how skin commensal bacteria interact with the immune system to promote tolerance in early life. The primary focus is on understanding how Toll-like receptor 2 (TLR2) sensing of modified ligands on Staphylococcus species supports the induction of commensal-specific regulatory T...
This Project Grant award of $242,310, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research at Weill Medical College of Cornell University aimed at understanding how the commensal microbiome interacts with the developing immune system in early life. The research seeks to elucidate the mechanisms by which select commensal bacteria are trafficked to the thymus, leading to the...
This federal Project Grant award, titled "EXPLOITING THE MICROBIOTA-STROMAL CELL AXIS FOR MICROBIOTA-TARGETED MEDICINE", is funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $466,500 award will support research to identify gut stromal cell populations and microbial components that influence B-cell development and antibody production in response to vaccination, with the goal of...
This Project Grant award, valued at $379,609.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The project aims to investigate how B cells establish tolerance to commensal microbial antigens, using a mouse model system expressing B cell receptors (BCRs) specific for a model commensal antigen, lipopolysaccharide (LPS). The research will formally define the mechanisms by which a ubiquitous...
This $107,948 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research to investigate the local and systemic coordination of antiviral immunity by tissue-resident memory CD8 T cells in the skin. The two-year project, running from February 1, 2025 to August 25, 2027, aims to determine whether CD8 tissue-resident memory T cells in the skin can orchestrate an immune...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a 2-year Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) worth $162,000 to The Johns Hopkins University to study how atypical B cells can be used to enhance vaccine responses in immunosuppressed individuals. The research project aims to define populations of immunosuppressed individuals who utilize these atypical CD11c+ B cells, assess their interaction with T cells, and target fatty acid oxidation...
This $2,002,422 Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to advance the understanding of systemic and mucosal immunity to vaccination and infection with enteric bacterial pathogens like Salmonella and Shigella in children and adults. The research will use human-based models and specimens from clinical studies to examine the mechanisms underlying...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $815,573 to The Leland Stanford Junior University (Stanford University) to study the mechanisms by which chronic, treated HIV infection drives inflammation in perinatally infected adolescents. The researchers will leverage a unique cohort of perinatally infected adolescents in Kenya, along with human lymphoid organoid models, to map...
This federal Project Grant award of $586,250 from the National Institute of Allergy and Infectious Diseases (NIAID) under CFDA 93.855 Allergy and Infectious Diseases Research program supports research to investigate how distinct age-associated B cell subsets can protect the aged from influenza. The project aims to determine the potential of different age-associated B cell subsets to respond to influenza infection and generate antibody-secreting cells, B cell memory, and long-lived...