Project Grant K23DK141365
- This federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to the University of Oklahoma Health Sciences Center. The $160,887 award supports research to investigate the role of injury-specific macrophages in acute kidney injury, a key contributor to kidney disease progression. The project aims to leverage single-cell RNA sequencing to...
- This $1,429,496 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) funds research to investigate the role of kidney blood flow shear stress in the development of systemic amyloidosis. The award, with a period of performance from September 2025 to May 2030, supports the use of microfluidic devices to replicate the shear stress conditions of the human...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $882,138 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Baylor College of Medicine. The grant, effective September 1, 2025 through June 30, 2030, will support the Houston Area Incubator for Kidney, Urologic and Hematologic Research Training (HAI-KUH). This program aims to develop a highly qualified workforce to improve the health and quality of...
- This Project Grant award of $155,562, awarded on December 11, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to elucidate the effect of activating branched chain amino acid (BCAA) catabolism in treating acute kidney injury (AKI) and preventing the transition to kidney fibrosis. The research will investigate metabolic changes in proximal tubule cells during AKI,...
- This Project Grant award for $532,177 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to investigate a new inflammation pathway in diabetic kidney disease (DKD), which is a leading cause of end-stage renal disease. The research aims to examine the role of the transcription modulator I-MFA in regulating inflammatory cytokine...
- This $400,000 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to understand the earliest events in podocyte injury in collagen IV nephropathies. The goal is to investigate how processing of mutant collagen IV proteins injures podocytes at early stages, leading to chronic kidney disease and renal failure. The research uses...
- This federal Project Grant award of $1,554,672, awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to define the molecular mechanisms of gut inflammation and barrier dysfunction in people with HIV. The research aims to investigate the role of the CARD8 inflammasome, which has been implicated in inflammatory bowel disease, in modulating gut...
- This $1,491,303 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research by The Washington University to investigate the role of cellular senescence in the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). The research aims to characterize how downregulation of the FOXM1-CCNF axis leads to cellular senescence and...
- This $168,886 Project Grant was awarded on May 1, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to The University of Texas Southwestern Medical Center in Dallas, TX. The 5-year grant will fund research to elucidate the role of NAD+ and PARP1 in fetal nephrogenesis, with the goal of understanding how maternal NAD+ deficiency can lead to reduced nephron endowment...
- This $243,750 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at the University of Pennsylvania to investigate the regulation of the DNA damage response in proximal tubule injury, which is an important contributor to chronic kidney disease. Key objectives include characterizing somatic copy number...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $201,084.00 to establish Molly Fisher, DO, MS as a translational investigator focused on understanding the role of chronic inflammation and senescence in kidney injury among people living with HIV. The award will support Dr. Fisher's training to develop expertise in urinary extracellular vesicle phenotyping for detecting early kidney injury, design and conduct translational studies leveraging cohort data and biospecimens, and acquire advanced biostatistics and bioinformatics skills. Dr. Fisher has assembled an expert mentorship team to guide this research, which aims to elucidate the mechanisms driving the elevated risk of acute and chronic kidney disease in the context of viral suppression among people with HIV.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $201.1k | 12/29/25 |